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PDBsum entry 2dwc
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protein ligands Protein-protein interface(s) links
Transferase PDB id
2dwc

 

 

 

 

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Contents
Protein chains
406 a.a. *
Ligands
SO4 ×4
ADP ×2
Waters ×519
* Residue conservation analysis
PDB id:
2dwc
Name: Transferase
Title: Crystal structure of probable phosphoribosylglycinamide formyl transferase from pyrococcus horikoshii ot3 complexed with adp
Structure: 433aa long hypothetical phosphoribosylglycinamide formyl transferase. Chain: a, b. Synonym: ph0318. Engineered: yes
Source: Pyrococcus horikoshii. Organism_taxid: 70601. Strain: ot3. Gene: ph0318. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
1.70Å     R-factor:   0.181     R-free:   0.204
Authors: S.Yoshikawa,R.Arai,T.Kamo-Uchikubo,M.Shirouzu,S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)
Key ref: S.Yoshikawa et al. Crystal structure of probable phosphoribosylglycinamide formyl transferase from pyrococcus horikoshii ot3 complexed with ADP. To be published, .
Date:
10-Aug-06     Release date:   10-Feb-07    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
O58056  (PURT_PYRHO) -  Formate-dependent phosphoribosylglycinamide formyltransferase from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Seq:
Struc: 		430 a.a.
406 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.6.3.1.21  - phosphoribosylglycinamide formyltransferase 2.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: N1-(5-phospho-beta-D-ribosyl)glycinamide + formate + ATP = N2-formyl- N1-(5-phospho-beta-D-ribosyl)glycinamide + ADP + phosphate + H+
N(1)-(5-phospho-beta-D-ribosyl)glycinamide
 + formate
 + ATP
 = N(2)-formyl- N(1)-(5-phospho-beta-D-ribosyl)glycinamide
Bound ligand (Het Group name = ADP)
corresponds exactly 		+ ADP
 + phosphate
 + H(+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

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