PDBsum entry 2db8

Protein binding

PDB id: 2db8

Contents

Protein chain

110 a.a. *

* Residue conservation analysis

PDB id:

2db8

Name:

Protein binding

Title:

Solution structures of the fn3 domain of human tripartite motif protein 9

Structure:

Tripartite motif protein 9, isoform 2. Chain: a. Fragment: fibronectin type iii domain. Synonym: tripartite motif protein 9. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: trim9. Expressed in: cell free synthesis. Other_details: cell-free protein synthesis

NMR struc:

20 models

Authors:

M.Sato,S.Koshiba,M.Inoue,T.Kigawa,S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

M.Sato et al. Solution structures of the fn3 domain of human tripartite motif protein 9. To be published, .

Date:

15-Dec-05 Release date: 15-Jun-06

Protein chain

Q9C026  (TRIM9_HUMAN) -  E3 ubiquitin-protein ligase TRIM9 from Homo sapiens

Seq: 710 a.a.

Struc: 110 a.a.*

* PDB and UniProt seqs differ at 13 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.2.3.2.27 - RING-type E3 ubiquitin transferase.
• Reaction: S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N₆- ubiquitinyl-[acceptor protein]-L-lysine