PDBsum entry 2cs5

Hydrolase

PDB id: 2cs5

Contents

Protein chain

119 a.a. *

* Residue conservation analysis

PDB id:

2cs5

Name:

Hydrolase

Title:

Solution structure of pdz domain of protein tyrosine phosphatase, non- receptor type 4

Structure:

Tyrosine-protein phosphatase, non-receptor type 4. Chain: a. Fragment: pdz domain. Synonym: protein-tyrosine phosphatase meg1, ptpase-meg1, meg. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn4. Other_details: cell-free protein synthesis

NMR struc:

20 models

Authors:

T.Nagashima,F.Hayashi,S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

T.Nagashima et al. Solution structure of pdz domain of protein tyrosine phosphatase, Non-Receptor type 4. To be published, .

Date:

20-May-05 Release date: 20-Nov-05

Protein chain

P29074  (PTN4_HUMAN) -  Tyrosine-protein phosphatase non-receptor type 4 from Homo sapiens

Seq: 926 a.a.

Struc: 119 a.a.*

* PDB and UniProt seqs differ at 13 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.3.1.3.48 - protein-tyrosine-phosphatase.
• Reaction: O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site