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PDBsum entry 2af7
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Contents |
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* Residue conservation analysis
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PDB id:
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Lyase
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Title:
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Crystal structure of the gamma-carboxymuconolactone decarboxylase from methanobacterium thermoautotrophicum. Northeast structural genomics consortium target tt747.
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Structure:
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Gamma-carboxymuconolactone decarboxylase. Chain: a, b, c, d, e, f, g, h, i. Engineered: yes
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Source:
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Methanothermobacter thermautotrophicus. Organism_taxid: 145262. Gene: mth234. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Biol. unit:
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Hexamer (from PDB file)
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Resolution:
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2.81Å
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R-factor:
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0.245
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R-free:
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0.292
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Authors:
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S.M.Vorobiev,A.Kuzin,T.Skarina,A.Savchenko,A.Semesi,C.Arrowsmith, A.Edwards,G.T.Montelione,L.Tong,Northeast Structural Genomics Consortium (Nesg)
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Key ref:
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S.M.Vorobiev
et al.
Crystal structure of the gamma-Carboxymuconolactone decarboxylase from methanobacterium thermoautotrophicum..
To be published,
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Date:
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25-Jul-05
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Release date:
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09-Aug-05
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PROCHECK
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Headers
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References
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O26336
(O26336_METTH) -
Gamma-carboxymuconolactone decarboxylase from Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
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Seq:
Struc:
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125 a.a.
119 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Enzyme class:
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E.C.4.1.1.44
- 4-carboxymuconolactone decarboxylase.
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Pathway:
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Benzoate Metabolism
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Reaction:
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(R)-2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate + H+ = (4,5-dihydro- 5-oxofuran-2-yl)-acetate + CO2
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(R)-2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate
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+
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H(+)
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=
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(4,5-dihydro- 5-oxofuran-2-yl)-acetate
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+
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CO2
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
