PDBsum entry 2a9e

Oxidoreductase

PDB id: 2a9e

Contents

Protein chains

491 a.a. *

Ligands

ACT

HEM-__O ×2

Waters ×884

* Residue conservation analysis

PDB id:

2a9e

Name:

Oxidoreductase

Title:

Helicobacter pylori catalase compound i

Structure:

Kata catalase. Chain: a, b. Engineered: yes

Source:

Helicobacter pylori. Organism_taxid: 210. Gene: kata. Expressed in: escherichia coli. Expression_system_taxid: 562.

Biol. unit:

Tetramer (from PDB file)

Resolution:

1.76Å R-factor: 0.139 R-free: 0.178

Authors:

P.C.Loewen,X.Carpena,I.Fita

Key ref:

P.C.Loewen et al. Helicobacter pylori catalase compound i. To be published, .

Date:

11-Jul-05 Release date: 20-Jun-06

Protein chains

P77872  (CATA_HELPY) -  Catalase from Helicobacter pylori (strain ATCC 700392 / 26695)

Seq: 505 a.a.

Struc: 492 a.a.*

* PDB and UniProt seqs differ at 10 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.1.11.1.6 - catalase.
• Reaction: 2 H2O2 = O2 + 2 H2O

2 × H2O2 (Bound ligand (Het Group name = ACT) matches with 50.00% similarity) = O2 + 2 × H2O

• Cofactor: Heme; Mn(2+)

Heme (Bound ligand (Het Group name = HEM) matches with 95.45% similarity) Mn(2+)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site