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PDBsum entry 2zx9
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Contents |
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* Residue conservation analysis
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PDB id:
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Hydrolase
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Title:
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Alpha-l-fucosidase complexed with inhibitor, b4
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Structure:
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Alpha-l-fucosidase, putative. Chain: a, b. Engineered: yes
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Source:
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Thermotoga maritima. Organism_taxid: 2336. Strain: msb8. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Resolution:
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2.62Å
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R-factor:
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0.162
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R-free:
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0.227
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Authors:
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H.-J.Wu,T.-P.Ko,C.-W.Ho,C.-H.Lin,A.H.-J.Wang
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Key ref:
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H.J.Wu
et al.
(2010).
Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range.
Angew Chem Int Ed Engl,
49,
337-340.
PubMed id:
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Date:
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22-Dec-08
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Release date:
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08-Dec-09
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PROCHECK
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Headers
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References
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Q9WYE2
(Q9WYE2_THEMA) -
Alpha-L-fucosidase, putative from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
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Seq:
Struc:
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449 a.a.
442 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Enzyme class:
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E.C.3.2.1.51
- alpha-L-fucosidase.
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Reaction:
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an alpha-L-fucoside + H2O = L-fucose + an alcohol
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alpha-L-fucoside
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+
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H2O
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=
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L-fucose
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+
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alcohol
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Angew Chem Int Ed Engl
49:337-340
(2010)
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PubMed id:
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Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range.
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H.J.Wu,
C.W.Ho,
T.P.Ko,
S.D.Popat,
C.H.Lin,
A.H.Wang.
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ABSTRACT
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Literature references that cite this PDB file's key reference
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PubMed id
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Reference
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A.Lammerts van Bueren,
S.D.Popat,
C.H.Lin,
and
G.J.Davies
(2010).
Structural and thermodynamic analyses of α-L-fucosidase inhibitors.
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Chembiochem,
11,
1971-1974.
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PDB codes:
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The most recent references are shown first.
Citation data come partly from CiteXplore and partly
from an automated harvesting procedure. Note that this is likely to be
only a partial list as not all journals are covered by
either method. However, we are continually building up the citation data
so more and more references will be included with time.
Where a reference describes a PDB structure, the PDB
codes are
shown on the right.
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Links
