PDBsum entry 2p2z

Hydrolase

PDB id: 2p2z

Contents

Protein chains

171 a.a. *

Ligands

GOL ×3

Metals

_NA

Waters ×365

* Residue conservation analysis

PDB id:

2p2z

Name:

Hydrolase

Title:

Crystal structure of tthb049 from thermus thermophilus hb8

Structure:

Alpha-ribazole-5'-phosphate phosphatase. Chain: a, b. Synonym: tthb049. Engineered: yes

Source:

Thermus thermophilus. Organism_taxid: 274. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Resolution:

1.75Å R-factor: 0.201 R-free: 0.228

Authors:

M.Sugahara,M.Taketa,Y.Tanaka,Y.Matsuura,N.Kunishima,Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

M.Sugahara et al. Crystal structure of tthb049 from thermus thermophilus hb8. To be published, .

Date:

08-Mar-07 Release date: 11-Sep-07

Protein chains

Q53WB3  (Q53WB3_THET8) -  Alpha-ribazole-5'-phosphate phosphatase from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)

Seq: 177 a.a.

Struc: 171 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.3.1.3.73 - adenosylcobalamin/alpha-ribazole phosphatase.
• Pathway: Corrin Biosynthesis (part 8)
• Reaction:
  1. adenosylcob(III)alamin 5'-phosphate + H2O = adenosylcob(III)alamin + phosphate
  2. alpha-ribazole 5'-phosphate + H2O = alpha-ribazole + phosphate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site