 |
PDBsum entry 2lu5
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Oxidoreductase
|
PDB id
|
|
|
|
2lu5
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PDB id:
|
|
|
|
| Name: |
|
Oxidoreductase
|
|
|
Title:
|
|
Structure and chemical shifts of cu(i),zn(ii) superoxide dismutase by solid-state nmr
|
|
Structure:
|
|
Superoxide dismutase [cu-zn]. Chain: a. Synonym: superoxide dismutase 1, hsod1. Engineered: yes. Mutation: yes
|
|
Source:
|
|
Homo sapiens. Human. Organism_taxid: 9606. Gene: sod1. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
NMR struc:
|
|
19 models
|
|
|
Authors:
|
|
M.J.Knight,A.J.Pell,I.Bertini,I.C.Felli,L.Gonnelli,R.Pierattelli, T.Herrmann,L.Emsley,G.Pintacuda
|
|
Key ref:
|
|
M.J.Knight
et al.
(2012).
Structure and backbone dynamics of a microcrystalline metalloprotein by solid-state NMR.
Proc Natl Acad Sci U S A,
109,
11095-11100.
PubMed id:
|
|
|
Date:
|
|
|
08-Jun-12
|
Release date:
|
27-Jun-12
|
|
|
|
|
|
|
PROCHECK
|
|
|
|
|
|
Headers
|
|
|
|
References
|
|
|
|
|
|
|
|
P00441
(SODC_HUMAN) -
Superoxide dismutase [Cu-Zn] from Homo sapiens
|
|
|
|
Seq:
Struc:
|
|
|
|
154 a.a.
153 a.a.*
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Key: |
 |
PfamA domain |
|
|
 |
Secondary structure |
|
 |
CATH domain |
|
|
*
PDB and UniProt seqs differ
at 2 residue positions (black
crosses)
|
|
|
|
|
|
|
|
|
|
|
|
|
Enzyme class:
|
|
E.C.1.15.1.1
- superoxide dismutase.
|
|
|
|
|
|
|
Reaction:
|
|
2 superoxide + 2 H+ = H2O2 + O2
|
|
|
|
|
|
2
×
superoxide
|
+
|
2
×
H(+)
|
=
|
H2O2
|
+
|
O2
|
|
|
|
|
|
|
|
|
|
Cofactor:
|
|
Fe cation or Mn(2+) or (Zn(2+) and Cu cation)
|
|
|
|
|
|
|
|
|
Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
|
|
|
|
|
|
| |
|
|
| |
|
|
Proc Natl Acad Sci U S A
109:11095-11100
(2012)
|
|
PubMed id:
|
|
|
|
|
|
| |
|
Structure and backbone dynamics of a microcrystalline metalloprotein by solid-state NMR.
|
|
M.J.Knight,
A.J.Pell,
I.Bertini,
I.C.Felli,
L.Gonnelli,
R.Pierattelli,
T.Herrmann,
L.Emsley,
G.Pintacuda.
|
|
|
|
|
| |
ABSTRACT
|
|
|
|
| |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
 |
 |
|
Links
