PDBsum entry 2gfq

Structural genomics, unknown function

PDB id: 2gfq

Contents

Protein chains

288 a.a. *

Ligands

SO4 ×17

Metals

_MG ×3

Waters ×1036

* Residue conservation analysis

PDB id:

2gfq

Name:

Structural genomics, unknown function

Title:

Structure of protein of unknown function ph0006 from pyrococcus horikoshii

Structure:

Upf0204 protein ph0006. Chain: a, b, c. Engineered: yes

Source:

Pyrococcus horikoshii. Organism_taxid: 70601. Strain: ot3. Gene: ph0006. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Resolution:

1.75Å R-factor: 0.152 R-free: 0.179

Authors:

M.E.Cuff,T.Skarina,E.Gorodichtchenskaia,A.Edwards,A.Savchenko, A.Joachimiak,Midwest Center For Structural Genomics (Mcsg)

Key ref:

M.E.Cuff et al. Structure of hypothetical protein ph0006 from pyrococcus horikoshii. To be published, .

Date:

22-Mar-06 Release date: 25-Apr-06

Protein chains

O57774  (DTDA_PYRHO) -  D-aminoacyl-tRNA deacylase from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)

Seq: 274 a.a.

Struc: 288 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.3.1.1.96 - D-aminoacyl-tRNA deacylase.
• Reaction:
  1. a D-aminoacyl-tRNA + H2O = a tRNA + a D-alpha-amino acid + H⁺
  2. glycyl-tRNA(Ala) + H2O = tRNA(Ala) + glycine + H⁺
• Cofactor: Zn(2+)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site