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PDBsum entry 1zjh
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Contents |
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* Residue conservation analysis
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PDB id:
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Transferase
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Title:
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Structure of human muscle pyruvate kinase (pkm2)
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Structure:
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Pyruvate kinase, isozymes m1/m2. Chain: a. Synonym: pyruvate kinase muscle isozyme, cytosolic thyroid hormone- binding protein, cthbp, thbp1. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: pkm2, pkm. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Biol. unit:
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Tetramer (from PDB file)
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Resolution:
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2.20Å
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R-factor:
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0.231
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R-free:
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0.279
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Authors:
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J.Choe,A.Atanassova,C.Arrowsmith,A.Edwards,M.Sundstrom,A.Bochkarev, H.Park,Structural Genomics Consortium (Sgc)
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Key ref:
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A.Atanassova
et al.
Structure of human muscle pyruvate kinase (pkm2)..
To be published,
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Date:
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28-Apr-05
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Release date:
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17-May-05
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PROCHECK
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Headers
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References
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P14618
(KPYM_HUMAN) -
Pyruvate kinase PKM from Homo sapiens
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Seq:
Struc:
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531 a.a.
507 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Enzyme class:
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E.C.2.7.1.40
- pyruvate kinase.
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Reaction:
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pyruvate + ATP = phosphoenolpyruvate + ADP + H+
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pyruvate
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+
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ATP
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=
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phosphoenolpyruvate
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+
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ADP
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+
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H(+)
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
