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PDBsum entry 1xhc

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protein ligands links
Oxidoreductase PDB id
1xhc

 

 

 

 

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Contents
Protein chain
346 a.a. *
Ligands
FAD
Waters ×31
* Residue conservation analysis
PDB id:
1xhc
Name: Oxidoreductase
Title: Nadh oxidase /nitrite reductase from pyrococcus furiosus pfu-1140779- 001
Structure: Nadh oxidase /nitrite reductase. Chain: a. Engineered: yes
Source: Pyrococcus furiosus. Organism_taxid: 186497. Strain: dsm 3638. Expressed in: escherichia coli. Expression_system_taxid: 562
Resolution:
2.35Å     R-factor:   0.202     R-free:   0.241
Authors: P.Horanyi,W.Tempel,M.V.Weinberg,Z.-J.Liu,A.Shah,L.Chen,D.Lee, F.J.Sugar,P.S.Brereton,M.Izumi,F.L.Poole Ii,C.Shah,F.E.Jenney Jr., W.B.Arendall Iii,J.P.Rose,M.W.W.Adams,J.S.Richardson,D.C.Richardson, B.-C.Wang,Southeast Collaboratory For Structural Genomics (Secsg)
Key ref: P.Horanyi et al. Nadh oxidase /nitrite reductase from pyrococcus furiosus pfu-1140779-001. To be published, .
Date:
17-Sep-04     Release date:   23-Nov-04    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q8U1K9  (Q8U1K9_PYRFU) -  NAD(P)H:rubredoxin oxidoreductase from Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Seq:
Struc:
359 a.a.
346 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Enzyme reactions 
   Enzyme class: E.C.1.18.1.4  - rubredoxin--NAD(P)(+) reductase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction:
1. 2 reduced [rubredoxin] + NADP+ + H+ = 2 oxidized [rubredoxin] + NADPH
2. 2 reduced [rubredoxin] + NAD+ + H+ = 2 oxidized [rubredoxin] + NADH
2 × reduced [rubredoxin]
+ NADP(+)
+ H(+)
= 2 × oxidized [rubredoxin]
+ NADPH
2 × reduced [rubredoxin]
+ NAD(+)
+ H(+)
= 2 × oxidized [rubredoxin]
+ NADH
      Cofactor: FAD
FAD
Bound ligand (Het Group name = FAD) corresponds exactly
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

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