PDBsum entry 1x2m

Transcription

PDB id: 1x2m

Contents

Protein chain

64 a.a. *

* Residue conservation analysis

PDB id:

1x2m

Name:

Transcription

Title:

Solution structure of the homeobox domain of mouse lag1 longevity assurance homolog 6

Structure:

Lag1 longevity assurance homolog 6. Chain: a. Fragment: homeobox domain. Engineered: yes

Source:

Mus musculus. House mouse. Organism_taxid: 10090. Gene: lass6. Other_details: cell-free protein synthesis

NMR struc:

20 models

Authors:

Y.O.Kamatari,T.Tomizawa,S.Koshiba,M.Inoue,T.Kigawa,S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

Y.O.Kamatari et al. Solution structure of the homeobox domain of mouse lag1 longevity assurance homolog 6. To be published, .

Date:

26-Apr-05 Release date: 26-Oct-05

Protein chain

Q8C172  (CERS6_MOUSE) -  Ceramide synthase 6 from Mus musculus

Seq: 384 a.a.

Struc: 64 a.a.*

* PDB and UniProt seqs differ at 12 residue positions (black crosses)

Enzyme reactions

• Enzyme class 1: E.C.2.3.1.- - ?????
• Enzyme class 2: E.C.2.3.1.291 - sphingoid base N-palmitoyltransferase.
• Reaction: a sphingoid base + hexadecanoyl-CoA = an N-hexadecanoyl-sphingoid base + CoA + H⁺

Note, where more than one E.C. class is given (as above), each may correspond to a different protein domain or, in the case of polyprotein precursors, to a different mature protein.

Molecule diagrams generated from .mol files obtained from the KEGG ftp site