PDBsum entry 1vf3

Transferase

PDB id: 1vf3

Contents

Protein chains

225 a.a. *

Ligands

GDN ×2

ACY

Waters ×211

* Residue conservation analysis

PDB id:

1vf3

Name:

Transferase

Title:

Cgsta1-1 in complex with glutathione conjugate of cdnb

Structure:

Glutathione s-transferase 3. Chain: a, b. Synonym: glutathione s-transferase a1-1, gst-cl3, gst class-alpha. Engineered: yes

Source:

Gallus gallus. Chicken. Organism_taxid: 9031. Gene: gta3. Expressed in: escherichia coli. Expression_system_taxid: 562.

Biol. unit:

Dimer (from PQS)

Resolution:

2.15Å R-factor: 0.217 R-free: 0.252

Authors:

S.C.Lin,Y.C.Lo,M.F.Tam,Y.C.Liaw

Key ref:

S.C.Lin et al. Crystal structures of chicken glutathione s-Transferase a1-1. To be published, .

Date:

07-Apr-04 Release date: 23-Aug-05

Protein chains

P26697  (GSTA3_CHICK) -  Glutathione S-transferase 3 from Gallus gallus

Seq: 229 a.a.

Struc: 225 a.a.

Enzyme reactions

• Enzyme class: E.C.2.5.1.18 - glutathione transferase.
• Reaction: RX + glutathione = an S-substituted glutathione + a halide anion + H⁺

RX (Bound ligand (Het Group name = GDN) matches with 62.50% similarity) + glutathione = S-substituted glutathione + halide anion + H(+)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site