PDBsum entry 1vcf

Isomerase

PDB id: 1vcf

Contents

Protein chains

299 a.a. *

Ligands

FMN ×2

Metals

_CD

* Residue conservation analysis

PDB id:

1vcf

Name:

Isomerase

Title:

Crystal structure of ipp isomerase at i422

Structure:

Isopentenyl-diphosphate delta-isomerase. Chain: a, b. Engineered: yes

Source:

Thermus thermophilus. Organism_taxid: 274. Expressed in: escherichia coli. Expression_system_taxid: 562.

Biol. unit:

Tetramer (from PDB file)

Resolution:

2.60Å R-factor: 0.242 R-free: 0.260

Authors:

T.Wada,S.-Y.Park,R.H.Tame,S.Kuramitsu,S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

T.Wada et al. Crystal structure of ipp isomerase at i422. To be published, .

Date:

08-Mar-04 Release date: 19-Apr-05

Protein chains

Q746I8  (IDI2_THET2) -  Isopentenyl-diphosphate delta-isomerase from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27)

Seq: 332 a.a.

Struc: 299 a.a.*

* PDB and UniProt seqs differ at 3 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.5.3.3.2 - isopentenyl-diphosphate Delta-isomerase.
• Pathway: Terpenoid biosynthesis
• Reaction: isopentenyl diphosphate = dimethylallyl diphosphate
• Cofactor: FMN or FAD; Mn(2+) or Mg(2+) or Ca(2+)

FMN (Bound ligand (Het Group name = FMN) corresponds exactly) or FAD Mn(2+) or Mg(2+) or Ca(2+)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site