PDBsum entry 1v9n

Oxidoreductase

PDB id: 1v9n

Contents

Protein chain

348 a.a. *

Ligands

NDP

GOL

Waters ×192

* Residue conservation analysis

PDB id:

1v9n

Name:

Oxidoreductase

Title:

Structure of malate dehydrogenase from pyrococcus horikoshii ot3

Structure:

Malate dehydrogenase. Chain: a. Engineered: yes

Source:

Pyrococcus horikoshii. Organism_taxid: 70601. Strain: ot3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Biol. unit:

Dimer (from PDB file)

Resolution:

2.10Å R-factor: 0.208 R-free: 0.243

Authors:

N.K.Lokanath,N.Kunishima,Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

N.K.Lokanath and n.kunishima Structure of malate dehydrogenase from pyrococcus horikoshii ot3. To be published, .

Date:

26-Jan-04 Release date: 29-Mar-05

Protein chain

O59028  (MDH_PYRHO) -  Malate dehydrogenase from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)

Seq: 360 a.a.

Struc: 348 a.a.

Enzyme reactions

• Enzyme class: E.C.1.1.1.37 - malate dehydrogenase.
• Pathway: Citric acid cycle
• Reaction: (S)-malate + NAD⁺ = oxaloacetate + NADH + H⁺

(S)-malate (Bound ligand (Het Group name = GOL) matches with 50.00% similarity) + NAD(+) (Bound ligand (Het Group name = NDP) matches with 91.67% similarity) = oxaloacetate + NADH + H(+)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site