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PDBsum entry 1v59
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protein ligands Protein-protein interface(s) links
Oxidoreductase PDB id
1v59

 

 

 

 

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Contents
Protein chains
478 a.a. *
Ligands
PO4
FAD ×2
NAD ×2
Waters ×407
* Residue conservation analysis
PDB id:
1v59
Name: Oxidoreductase
Title: Crystal structure of yeast lipoamide dehydrogenase complexed with NAD+
Structure: Dihydrolipoamide dehydrogenase. Chain: a, b. Ec: 1.8.1.4
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932
Biol. unit: Dimer (from PQS)
Resolution:
2.20Å     R-factor:   0.203     R-free:   0.246
Authors: W.Adachi,K.Suzuki,M.Tsunoda,T.Sekiguchi,L.J.Reed,A.Takenaka
Key ref: W.Adachi et al. Crystal structure of yeast lipoamide dehydrogenase complexed with NAD+. To be published, .
Date:
21-Nov-03     Release date:   15-Feb-05    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P09624  (DLDH_YEAST) -  Dihydrolipoyl dehydrogenase, mitochondrial from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Seq:
Struc: 		499 a.a.
478 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.1.8.1.4  - dihydrolipoyl dehydrogenase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway: 		Glycine Cleavage System
      Reaction: N6-[(R)-dihydrolipoyl]-L-lysyl-[protein] + NAD+ = N6-[(R)-lipoyl]- L-lysyl-[protein] + NADH + H+
N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein]
 + NAD(+)
 = N(6)-[(R)-lipoyl]- L-lysyl-[protein]
 + NADH
 + H(+)
      Cofactor: FAD
FAD
Bound ligand (Het Group name = FAD) corresponds exactly
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

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