PDBsum entry 1onh

Hydrolase

PDB id: 1onh

Contents

Protein chain

363 a.a. *

Ligands

WY4

GOL ×4

Waters ×427

* Residue conservation analysis

PDB id:

1onh

Name:

Hydrolase

Title:

Gc1 beta-lactamase with a penem inhibitor

Structure:

Class c beta-lactamase. Chain: a. Engineered: yes

Source:

Enterobacter cloacae. Organism_taxid: 550. Gene: blac. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.38Å R-factor: 0.138 R-free: 0.202

Authors:

M.Nukaga,K.Nukaga,J.R.Knox

Date:

27-Feb-03 Release date: 09-Dec-03

Protein chain

Q59401  (Q59401_ENTCL) -  Beta-lactamase from Enterobacter cloacae

Seq: 384 a.a.

Struc: 363 a.a.

Enzyme reactions

• Enzyme class: E.C.3.5.2.6 - beta-lactamase.
• Pathway: Penicillin Biosynthesis and Metabolism
• Reaction: a beta-lactam + H2O = a substituted beta-amino acid
• Cofactor: Zn(2+)