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PDBsum entry 1mfb

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Immunoglobulin PDB id
1mfb

 

 

 

 

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Contents
Protein chains
212 a.a. *
212 a.a. *
Ligands
RAM-MAN-GLA-RAM-
MAN-GLA-ABE
Waters ×256
* Residue conservation analysis
PDB id:
1mfb
Name: Immunoglobulin
Title: High resolution structures of antibody fab fragment complexed with cell-surface oligosaccharide of pathogenic salmonella
Structure: Igg1-lambda se155-4 fab (light chain). Chain: l. Engineered: yes. Igg1-lambda se155-4 fab (heavy chain). Chain: h. Engineered: yes
Source: Mus musculus. House mouse. Organism_taxid: 10090. Organism_taxid: 10090
Biol. unit: Dimer (from PQS)
Resolution:
2.10Å     R-factor:   0.160    
Authors: A.Zdanov,M.Cygler
Key ref: M.Cygler et al. (1993). Recognition of a carbohydrate antigenic determinant of Salmonella by an antibody. Biochem Soc Trans, 21, 437-441. PubMed id: 7689495
Date:
25-Oct-93     Release date:   31-Jan-94    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
No UniProt id for this chain
Struc: 212 a.a.
Protein chain
No UniProt id for this chain
Struc: 212 a.a.
Key:    Secondary structure  CATH domain

 

 
Biochem Soc Trans 21:437-441 (1993)
PubMed id: 7689495  
 
 
Recognition of a carbohydrate antigenic determinant of Salmonella by an antibody.
M.Cygler, S.Wu, A.Zdanov, D.R.Bundle, D.R.Rose.
 
  ABSTRACT  
 
No abstract given.

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
18621718 B.Vulliez-Le Normand, F.A.Saul, A.Phalipon, F.Bélot, C.Guerreiro, L.A.Mulard, and G.A.Bentley (2008).
Structures of synthetic O-antigen fragments from serotype 2a Shigella flexneri in complex with a protective monoclonal antibody.
  Proc Natl Acad Sci U S A, 105, 9976-9981.
PDB codes: 3bz4 3c5s 3c6s
18806257 T.K.Dam, M.Torres, C.F.Brewer, and A.Casadevall (2008).
Isothermal Titration Calorimetry Reveals Differential Binding Thermodynamics of Variable Region-identical Antibodies Differing in Constant Region for a Univalent Ligand.
  J Biol Chem, 283, 31366-31370.  
14627696 U.Krengel, L.L.Olsson, C.Martínez, A.Talavera, G.Rojas, E.Mier, J.Angström, and E.Moreno (2004).
Structure and molecular interactions of a unique antitumor antibody specific for N-glycolyl GM3.
  J Biol Chem, 279, 5597-5603.
PDB code: 1rih
10880560 S.Villeneuve, H.Souchon, M.M.Riottot, J.C.Mazie, P.Lei, C.P.Glaudemans, P.Kovác, J.M.Fournier, and P.M.Alzari (2000).
Crystal structure of an anti-carbohydrate antibody directed against Vibrio cholerae O1 in complex with antigen: molecular basis for serotype specificity.
  Proc Natl Acad Sci U S A, 97, 8433-8438.
PDB codes: 1f4w 1f4x 1f4y
9195884 K.Sorimachi, M.F.Le Gal-Coëffet, G.Williamson, D.B.Archer, and M.P.Williamson (1997).
Solution structure of the granular starch binding domain of Aspergillus niger glucoamylase bound to beta-cyclodextrin.
  Structure, 5, 647-661.
PDB codes: 1ac0 1acz
8855221 S.Steinbacher, U.Baxa, S.Miller, A.Weintraub, R.Seckler, and R.Huber (1996).
Crystal structure of phage P22 tailspike protein complexed with Salmonella sp. O-antigen receptors.
  Proc Natl Acad Sci U S A, 93, 10584-10588.
PDB codes: 1tyu 1tyv 1tyw 1tyx
7517550 A.Zdanov, Y.Li, D.R.Bundle, S.J.Deng, C.R.MacKenzie, S.A.Narang, N.M.Young, and M.Cygler (1994).
Structure of a single-chain antibody variable domain (Fv) fragment complexed with a carbohydrate antigen at 1.7-A resolution.
  Proc Natl Acad Sci U S A, 91, 6423-6427.
PDB code: 1mfa
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time. Where a reference describes a PDB structure, the PDB codes are shown on the right.

 

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