spacer
spacer

PDBsum entry 1kq4
Go to PDB code: 
protein ligands Protein-protein interface(s) links
Transferase PDB id
1kq4

 

 

 

 

Loading ...

 
JSmol PyMol  
Contents
Protein chains
203 a.a. *
214 a.a. *
Ligands
FAD ×4
Waters ×274
* Residue conservation analysis
PDB id:
1kq4
Name: Transferase
Title: Crystal structure of a thy1-complementing protein (tm0449) from thermotoga maritima at 2.25 a resolution
Structure: Hypothetical protein tm0449. Chain: a, b, c, d. Engineered: yes
Source: Thermotoga maritima. Organism_taxid: 2336. Gene: tm0449. Expressed in: escherichia coli. Expression_system_taxid: 562.
Biol. unit: Tetramer (from PQS)
Resolution:
2.25Å     R-factor:   0.192     R-free:   0.240
Authors: I.A.Wilson,M.D.Miller,Joint Center For Structural Genomics (Jcsg)
Key ref:
S.A.Lesley et al. (2002). Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline. Proc Natl Acad Sci U S A, 99, 11664-11669. PubMed id: 12193646 DOI: 10.1073/pnas.142413399
Date:
03-Jan-02     Release date:   27-Feb-02    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q9WYT0  (THYX_THEMA) -  Flavin-dependent thymidylate synthase from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
Seq:
Struc: 		220 a.a.
203 a.a.
Protein chains
Pfam   ArchSchema ?
Q9WYT0  (THYX_THEMA) -  Flavin-dependent thymidylate synthase from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
Seq:
Struc: 		220 a.a.
214 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: Chains A, B, C, D: E.C.2.1.1.148  - thymidylate synthase (FAD).
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: dUMP + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADPH + H+ = dTMP + (6S)-5,6,7,8-tetrahydrofolate + NADP+
dUMP
 + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate
 + NADPH
 + H(+)
Bound ligand (Het Group name = FAD)
matches with 71.19% similarity 		= dTMP
 + (6S)-5,6,7,8-tetrahydrofolate
 + NADP(+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

 
    reference    
 
 
DOI no: 10.1073/pnas.142413399 Proc Natl Acad Sci U S A 99:11664-11669 (2002)
PubMed id: 12193646  
 
 
Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline.
S.A.Lesley, P.Kuhn, A.Godzik, A.M.Deacon, I.Mathews, A.Kreusch, G.Spraggon, H.E.Klock, D.McMullan, T.Shin, J.Vincent, A.Robb, L.S.Brinen, M.D.Miller, T.M.McPhillips, M.A.Miller, D.Scheibe, J.M.Canaves, C.Guda, L.Jaroszewski, T.L.Selby, M.A.Elsliger, J.Wooley, S.S.Taylor, K.O.Hodgson, I.A.Wilson, P.G.Schultz, R.C.Stevens.
 
  ABSTRACT  
 
Structural genomics is emerging as a principal approach to define protein structure-function relationships. To apply this approach on a genomic scale, novel methods and technologies must be developed to determine large numbers of structures. We describe the design and implementation of a high-throughput structural genomics pipeline and its application to the proteome of the thermophilic bacterium Thermotoga maritima. By using this pipeline, we successfully cloned and attempted expression of 1,376 of the predicted 1,877 genes (73%) and have identified crystallization conditions for 432 proteins, comprising 23% of the T. maritima proteome. Representative structures from TM0423 glycerol dehydrogenase and TM0449 thymidylate synthase-complementing protein are presented as examples of final outputs from the pipeline.
 
  Selected figure(s)  
 
Figure 1.
Fig. 1. T. maritima structural genomics pipeline. 		Figure 2.
Fig. 2. Custom instrumentation used to process T. maritima proteome. (A) A 96-tube fermentor for high-cell density growth. (B) Purification robot that processes cell pellets from fermentation through affinity purification. (C) Nano-drop crystallization robotics used to set up crystal trials. (D) Plate imaging robotics used to analyze crystal trials.
 
  Figures were selected by an automated process.  

Literature references that cite this PDB file's key reference

  PubMed id Reference
21445265 D.Das, M.Hervé, J.Feuerhelm, C.L.Farr, H.J.Chiu, M.A.Elsliger, M.W.Knuth, H.E.Klock, M.D.Miller, A.Godzik, S.A.Lesley, A.M.Deacon, D.Mengin-Lecreulx, and I.A.Wilson (2011).
Structure and function of the first full-length murein peptide ligase (Mpl) cell wall recycling protein.
  PLoS One, 6, e17624.
PDB code: 3hn7
21082721 G.J.Forse, N.Ram, D.R.Banatao, D.Cascio, M.R.Sawaya, H.E.Klock, S.A.Lesley, and T.O.Yeates (2011).
Synthetic symmetrization in the crystallization and structure determination of CelA from Thermotoga maritima.
  Protein Sci, 20, 168-178.
PDB code: 3o7o
21247902 J.Hwang, Y.Kim, H.B.Kang, L.Jaroszewski, A.M.Deacon, H.Lee, W.C.Choi, K.J.Kim, C.H.Kim, B.S.Kang, J.O.Lee, T.K.Oh, J.W.Kim, I.A.Wilson, and M.H.Kim (2011).
Crystal structure of the human N-Myc downstream-regulated gene 2 protein provides insight into its role as a tumor suppressor.
  J Biol Chem, 286, 12450-12460.
PDB codes: 2qmq 2xmq 2xmr 2xms
  20944218 A.Kumar, A.Lomize, K.K.Jin, D.Carlton, M.D.Miller, L.Jaroszewski, P.Abdubek, T.Astakhova, H.L.Axelrod, H.J.Chiu, T.Clayton, D.Das, M.C.Deller, L.Duan, J.Feuerhelm, J.C.Grant, A.Grzechnik, G.W.Han, H.E.Klock, M.W.Knuth, P.Kozbial, S.S.Krishna, D.Marciano, D.McMullan, A.T.Morse, E.Nigoghossian, L.Okach, R.Reyes, C.L.Rife, N.Sefcovic, H.J.Tien, C.B.Trame, H.van den Bedem, D.Weekes, Q.Xu, K.O.Hodgson, J.Wooley, M.A.Elsliger, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2010).
Open and closed conformations of two SpoIIAA-like proteins (YP_749275.1 and YP_001095227.1) provide insights into membrane association and ligand binding.
  Acta Crystallogr Sect F Struct Biol Cryst Commun, 66, 1245-1253.
PDB codes: 2ook 2q3l
  20944224 A.P.Yeh, P.Abdubek, T.Astakhova, H.L.Axelrod, C.Bakolitsa, X.Cai, D.Carlton, C.Chen, H.J.Chiu, M.Chiu, T.Clayton, D.Das, M.C.Deller, L.Duan, K.Ellrott, C.L.Farr, J.Feuerhelm, J.C.Grant, A.Grzechnik, G.W.Han, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, P.Kozbial, S.S.Krishna, A.Kumar, W.W.Lam, D.Marciano, D.McMullan, M.D.Miller, A.T.Morse, E.Nigoghossian, A.Nopakun, L.Okach, C.Puckett, R.Reyes, H.J.Tien, C.B.Trame, H.van den Bedem, D.Weekes, T.Wooten, Q.Xu, K.O.Hodgson, J.Wooley, M.A.Elsliger, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2010).
Structure of Bacteroides thetaiotaomicron BT2081 at 2.05 Šresolution: the first structural representative of a new protein family that may play a role in carbohydrate metabolism.
  Acta Crystallogr Sect F Struct Biol Cryst Commun, 66, 1287-1296.
PDB code: 3hbz
22184477 C.A.Smith, G.L.Card, A.E.Cohen, T.I.Doukov, T.Eriksson, A.M.Gonzalez, S.E.McPhillips, P.W.Dunten, I.I.Mathews, J.Song, and S.M.Soltis (2010).
Remote access to crystallography beamlines at SSRL: novel tools for training, education and collaboration.
  J Appl Crystallogr, 43, 1261-1270.  
  20944211 C.Bakolitsa, A.Bateman, K.K.Jin, D.McMullan, S.S.Krishna, M.D.Miller, P.Abdubek, C.Acosta, T.Astakhova, H.L.Axelrod, P.Burra, D.Carlton, H.J.Chiu, T.Clayton, D.Das, M.C.Deller, L.Duan, Y.Elias, J.Feuerhelm, J.C.Grant, A.Grzechnik, S.K.Grzechnik, G.W.Han, L.Jaroszewski, H.E.Klock, M.W.Knuth, P.Kozbial, A.Kumar, D.Marciano, A.T.Morse, K.D.Murphy, E.Nigoghossian, L.Okach, S.Oommachen, J.Paulsen, R.Reyes, C.L.Rife, N.Sefcovic, H.Tien, C.B.Trame, C.V.Trout, H.van den Bedem, D.Weekes, A.White, Q.Xu, K.O.Hodgson, J.Wooley, M.A.Elsliger, A.M.Deacon, A.Godzik, S.Lesley, and I.A.Wilson (2010).
The structure of Jann_2411 (DUF1470) from Jannaschia sp. at 1.45 Šresolution reveals a new fold (the ABATE domain) and suggests its possible role as a transcription regulator.
  Acta Crystallogr Sect F Struct Biol Cryst Commun, 66, 1198-1204.
PDB code: 3h0n
  20944212 C.Bakolitsa, A.Kumar, D.Carlton, M.D.Miller, S.S.Krishna, P.Abdubek, T.Astakhova, H.L.Axelrod, H.J.Chiu, T.Clayton, M.C.Deller, L.Duan, M.A.Elsliger, J.Feuerhelm, S.K.Grzechnik, J.C.Grant, G.W.Han, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, P.Kozbial, D.Marciano, D.McMullan, A.T.Morse, E.Nigoghossian, L.Okach, S.Oommachen, J.Paulsen, R.Reyes, C.L.Rife, H.J.Tien, C.V.Trout, H.van den Bedem, D.Weekes, Q.Xu, K.O.Hodgson, J.Wooley, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2010).
Structure of LP2179, the first representative of Pfam family PF08866, suggests a new fold with a role in amino-acid metabolism.
  Acta Crystallogr Sect F Struct Biol Cryst Commun, 66, 1205-1210.
PDB code: 2iay
  20944213 C.Bakolitsa, A.Kumar, D.McMullan, S.S.Krishna, M.D.Miller, D.Carlton, R.Najmanovich, P.Abdubek, T.Astakhova, H.J.Chiu, T.Clayton, M.C.Deller, L.Duan, Y.Elias, J.Feuerhelm, J.C.Grant, S.K.Grzechnik, G.W.Han, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, P.Kozbial, D.Marciano, A.T.Morse, E.Nigoghossian, L.Okach, S.Oommachen, J.Paulsen, R.Reyes, C.L.Rife, C.V.Trout, H.van den Bedem, D.Weekes, A.White, Q.Xu, K.O.Hodgson, J.Wooley, M.A.Elsliger, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2010).
The structure of the first representative of Pfam family PF06475 reveals a new fold with possible involvement in glycolipid metabolism.
  Acta Crystallogr Sect F Struct Biol Cryst Commun, 66, 1211-1217.
PDB code: 2h1t
  20944209 C.Bakolitsa, A.Kumar, K.K.Jin, D.McMullan, S.S.Krishna, M.D.Miller, P.Abdubek, C.Acosta, T.Astakhova, H.L.Axelrod, P.Burra, D.Carlton, C.Chen, H.J.Chiu, T.Clayton, D.Das, M.C.Deller, L.Duan, Y.Elias, K.Ellrott, D.Ernst, C.L.Farr, J.Feuerhelm, J.C.Grant, A.Grzechnik, S.K.Grzechnik, G.W.Han, L.Jaroszewski, H.A.Johnson, H.E.Klock, M.W.Knuth, P.Kozbial, D.Marciano, A.T.Morse, K.D.Murphy, E.Nigoghossian, A.Nopakun, L.Okach, J.Paulsen, C.Puckett, R.Reyes, C.L.Rife, N.Sefcovic, H.J.Tien, C.B.Trame, C.V.Trout, H.van den Bedem, D.Weekes, A.White, Q.Xu, K.O.Hodgson, J.Wooley, M.A.Elsliger, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2010).
Structures of the first representatives of Pfam family PF06684 (DUF1185) reveal a novel variant of the Bacillus chorismate mutase fold and suggest a role in amino-acid metabolism.
  Acta Crystallogr Sect F Struct Biol Cryst Commun, 66, 1182-1189.
PDB codes: 2qtp 3byq
  20944222 C.Bakolitsa, Q.Xu, C.L.Rife, P.Abdubek, T.Astakhova, H.L.Axelrod, D.Carlton, C.Chen, H.J.Chiu, T.Clayton, D.Das, M.C.Deller, L.Duan, K.Ellrott, C.L.Farr, J.Feuerhelm, J.C.Grant, A.Grzechnik, G.W.Han, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, P.Kozbial, S.S.Krishna, A.Kumar, W.W.Lam, D.Marciano, D.McMullan, M.D.Miller, A.T.Morse, E.Nigoghossian, A.Nopakun, L.Okach, C.Puckett, R.Reyes, H.J.Tien, C.B.Trame, H.van den Bedem, D.Weekes, K.O.Hodgson, J.Wooley, M.A.Elsliger, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2010).
Structure of BT_3984, a member of the SusD/RagB family of nutrient-binding molecules.
  Acta Crystallogr Sect F Struct Biol Cryst Commun, 66, 1274-1280.
PDB code: 3cgh
20122942 D.Das, D.Moiani, H.L.Axelrod, M.D.Miller, D.McMullan, K.K.Jin, P.Abdubek, T.Astakhova, P.Burra, D.Carlton, H.J.Chiu, T.Clayton, M.C.Deller, L.Duan, D.Ernst, J.Feuerhelm, J.C.Grant, A.Grzechnik, S.K.Grzechnik, G.W.Han, L.Jaroszewski, H.E.Klock, M.W.Knuth, P.Kozbial, S.S.Krishna, A.Kumar, D.Marciano, A.T.Morse, E.Nigoghossian, L.Okach, J.Paulsen, R.Reyes, C.L.Rife, N.Sefcovic, H.J.Tien, C.B.Trame, H.van den Bedem, D.Weekes, Q.Xu, K.O.Hodgson, J.Wooley, M.A.Elsliger, A.M.Deacon, A.Godzik, S.A.Lesley, J.A.Tainer, and I.A.Wilson (2010).
Crystal structure of the first eubacterial Mre11 nuclease reveals novel features that may discriminate substrates during DNA repair.
  J Mol Biol, 397, 647-663.
PDB code: 2q8u
  20944208 D.Das, N.V.Grishin, A.Kumar, D.Carlton, C.Bakolitsa, M.D.Miller, P.Abdubek, T.Astakhova, H.L.Axelrod, P.Burra, C.Chen, H.J.Chiu, M.Chiu, T.Clayton, M.C.Deller, L.Duan, K.Ellrott, D.Ernst, C.L.Farr, J.Feuerhelm, A.Grzechnik, S.K.Grzechnik, J.C.Grant, G.W.Han, L.Jaroszewski, K.K.Jin, H.A.Johnson, H.E.Klock, M.W.Knuth, P.Kozbial, S.S.Krishna, D.Marciano, D.McMullan, A.T.Morse, E.Nigoghossian, A.Nopakun, L.Okach, S.Oommachen, J.Paulsen, C.Puckett, R.Reyes, C.L.Rife, N.Sefcovic, H.J.Tien, C.B.Trame, H.van den Bedem, D.Weekes, T.Wooten, Q.Xu, K.O.Hodgson, J.Wooley, M.A.Elsliger, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2010).
The structure of the first representative of Pfam family PF09836 reveals a two-domain organization and suggests involvement in transcriptional regulation.
  Acta Crystallogr Sect F Struct Biol Cryst Commun, 66, 1174-1181.
PDB code: 3dee
  20944219 D.Das, P.Kozbial, G.W.Han, D.Carlton, L.Jaroszewski, P.Abdubek, T.Astakhova, H.L.Axelrod, C.Bakolitsa, C.Chen, H.J.Chiu, M.Chiu, T.Clayton, M.C.Deller, L.Duan, K.Ellrott, M.A.Elsliger, D.Ernst, C.L.Farr, J.Feuerhelm, A.Grzechnik, J.C.Grant, K.K.Jin, H.A.Johnson, H.E.Klock, M.W.Knuth, S.S.Krishna, A.Kumar, D.Marciano, D.McMullan, M.D.Miller, A.T.Morse, E.Nigoghossian, A.Nopakun, L.Okach, S.Oommachen, J.Paulsen, C.Puckett, R.Reyes, C.L.Rife, N.Sefcovic, H.J.Tien, C.B.Trame, H.van den Bedem, D.Weekes, T.Wooten, Q.Xu, K.O.Hodgson, J.Wooley, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2010).
The structure of KPN03535 (gi|152972051), a novel putative lipoprotein from Klebsiella pneumoniae, reveals an OB-fold.
  Acta Crystallogr Sect F Struct Biol Cryst Commun, 66, 1254-1260.
PDB code: 3f1z
  20944221 D.Das, R.D.Finn, D.Carlton, M.D.Miller, P.Abdubek, T.Astakhova, H.L.Axelrod, C.Bakolitsa, C.Chen, H.J.Chiu, M.Chiu, T.Clayton, M.C.Deller, L.Duan, K.Ellrott, D.Ernst, C.L.Farr, J.Feuerhelm, J.C.Grant, A.Grzechnik, G.W.Han, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, P.Kozbial, S.S.Krishna, A.Kumar, D.Marciano, D.McMullan, A.T.Morse, E.Nigoghossian, A.Nopakun, L.Okach, C.Puckett, R.Reyes, C.L.Rife, N.Sefcovic, H.J.Tien, C.B.Trame, H.van den Bedem, D.Weekes, T.Wooten, Q.Xu, K.O.Hodgson, J.Wooley, M.A.Elsliger, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2010).
The structure of BVU2987 from Bacteroides vulgatus reveals a superfamily of bacterial periplasmic proteins with possible inhibitory function.
  Acta Crystallogr Sect F Struct Biol Cryst Commun, 66, 1265-1273.
PDB code: 3due
20836087 D.Das, R.D.Finn, P.Abdubek, T.Astakhova, H.L.Axelrod, C.Bakolitsa, X.Cai, D.Carlton, C.Chen, H.J.Chiu, M.Chiu, T.Clayton, M.C.Deller, L.Duan, K.Ellrott, C.L.Farr, J.Feuerhelm, J.C.Grant, A.Grzechnik, G.W.Han, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, P.Kozbial, S.S.Krishna, A.Kumar, W.W.Lam, D.Marciano, M.D.Miller, A.T.Morse, E.Nigoghossian, A.Nopakun, L.Okach, C.Puckett, R.Reyes, H.J.Tien, C.B.Trame, H.van den Bedem, D.Weekes, T.Wooten, Q.Xu, A.Yeh, J.Zhou, K.O.Hodgson, J.Wooley, M.A.Elsliger, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2010).
The crystal structure of a bacterial Sufu-like protein defines a novel group of bacterial proteins that are similar to the N-terminal domain of human Sufu.
  Protein Sci, 19, 2131-2140.
PDB code: 3k5j
20077512 E.D.Scheeff, H.L.Axelrod, M.D.Miller, H.J.Chiu, A.M.Deacon, I.A.Wilson, and G.Manning (2010).
Genomics, evolution, and crystal structure of a new family of bacterial spore kinases.
  Proteins, 78, 1470-1482.
PDB code: 2q83
19643076 E.M.Koehn, and A.Kohen (2010).
Flavin-dependent thymidylate synthase: a novel pathway towards thymine.
  Arch Biochem Biophys, 493, 96.  
20559564 G.Spraggon, E.Koesema, M.Scarselli, E.Malito, M.Biagini, N.Norais, C.Emolo, M.A.Barocchi, F.Giusti, M.Hilleringmann, R.Rappuoli, S.Lesley, A.Covacci, V.Masignani, and I.Ferlenghi (2010).
Supramolecular organization of the repetitive backbone unit of the Streptococcus pneumoniae pilus.
  PLoS One, 5, e10919.
PDB codes: 2x9w 2x9x 2x9y 2x9z
  20944214 G.W.Han, C.Bakolitsa, M.D.Miller, A.Kumar, D.Carlton, R.J.Najmanovich, P.Abdubek, T.Astakhova, H.L.Axelrod, C.Chen, H.J.Chiu, T.Clayton, D.Das, M.C.Deller, L.Duan, D.Ernst, J.Feuerhelm, J.C.Grant, A.Grzechnik, L.Jaroszewski, K.K.Jin, H.A.Johnson, H.E.Klock, M.W.Knuth, P.Kozbial, S.S.Krishna, D.Marciano, D.McMullan, A.T.Morse, E.Nigoghossian, L.Okach, R.Reyes, C.L.Rife, N.Sefcovic, H.J.Tien, C.B.Trame, H.van den Bedem, D.Weekes, Q.Xu, K.O.Hodgson, J.Wooley, M.A.Elsliger, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2010).
Structures of the first representatives of Pfam family PF06938 (DUF1285) reveal a new fold with repeated structural motifs and possible involvement in signal transduction.
  Acta Crystallogr Sect F Struct Biol Cryst Commun, 66, 1218-1225.
PDB codes: 2ra9 2re3
  20944217 G.W.Han, M.A.Elsliger, T.O.Yeates, Q.Xu, A.G.Murzin, S.S.Krishna, L.Jaroszewski, P.Abdubek, T.Astakhova, H.L.Axelrod, D.Carlton, C.Chen, H.J.Chiu, T.Clayton, D.Das, M.C.Deller, L.Duan, D.Ernst, J.Feuerhelm, J.C.Grant, A.Grzechnik, K.K.Jin, H.A.Johnson, H.E.Klock, M.W.Knuth, P.Kozbial, A.Kumar, W.W.Lam, D.Marciano, D.McMullan, M.D.Miller, A.T.Morse, E.Nigoghossian, L.Okach, R.Reyes, C.L.Rife, N.Sefcovic, H.J.Tien, C.B.Trame, H.van den Bedem, D.Weekes, K.O.Hodgson, J.Wooley, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2010).
Structure of a putative NTP pyrophosphohydrolase: YP_001813558.1 from Exiguobacterium sibiricum 255-15.
  Acta Crystallogr Sect F Struct Biol Cryst Commun, 66, 1237-1244.
PDB code: 3nl9
  20944229 G.W.Han, X.L.Yang, D.McMullan, Y.E.Chong, S.S.Krishna, C.L.Rife, D.Weekes, S.M.Brittain, P.Abdubek, E.Ambing, T.Astakhova, H.L.Axelrod, D.Carlton, J.Caruthers, H.J.Chiu, T.Clayton, L.Duan, J.Feuerhelm, J.C.Grant, S.K.Grzechnik, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, A.Kumar, D.Marciano, M.D.Miller, A.T.Morse, E.Nigoghossian, L.Okach, J.Paulsen, R.Reyes, H.van den Bedem, A.White, G.Wolf, Q.Xu, K.O.Hodgson, J.Wooley, A.M.Deacon, A.Godzik, S.A.Lesley, M.A.Elsliger, P.Schimmel, and I.A.Wilson (2010).
Structure of a tryptophanyl-tRNA synthetase containing an iron-sulfur cluster.
  Acta Crystallogr Sect F Struct Biol Cryst Commun, 66, 1326-1334.
PDB code: 2g36
  20944205 H.J.Chiu, C.Bakolitsa, A.Skerra, A.Lomize, D.Carlton, M.D.Miller, S.S.Krishna, P.Abdubek, T.Astakhova, H.L.Axelrod, T.Clayton, M.C.Deller, L.Duan, J.Feuerhelm, J.C.Grant, S.K.Grzechnik, G.W.Han, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, P.Kozbial, A.Kumar, D.Marciano, D.McMullan, A.T.Morse, E.Nigoghossian, L.Okach, J.Paulsen, R.Reyes, C.L.Rife, H.van den Bedem, D.Weekes, Q.Xu, K.O.Hodgson, J.Wooley, M.A.Elsliger, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2010).
Structure of the first representative of Pfam family PF09410 (DUF2006) reveals a structural signature of the calycin superfamily that suggests a role in lipid metabolism.
  Acta Crystallogr Sect F Struct Biol Cryst Commun, 66, 1153-1159.
PDB code: 2ich
  20944228 H.J.Chiu, P.Abdubek, T.Astakhova, H.L.Axelrod, D.Carlton, T.Clayton, D.Das, M.C.Deller, L.Duan, J.Feuerhelm, J.C.Grant, A.Grzechnik, G.W.Han, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, P.Kozbial, S.S.Krishna, A.Kumar, D.Marciano, D.McMullan, M.D.Miller, A.T.Morse, E.Nigoghossian, L.Okach, R.Reyes, H.J.Tien, C.B.Trame, H.van den Bedem, D.Weekes, Q.Xu, K.O.Hodgson, J.Wooley, M.A.Elsliger, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2010).
The structure of Haemophilus influenzae prephenate dehydrogenase suggests unique features of bifunctional TyrA enzymes.
  Acta Crystallogr Sect F Struct Biol Cryst Commun, 66, 1317-1325.
PDB code: 2pv7
  20944230 H.L.Axelrod, D.Das, P.Abdubek, T.Astakhova, C.Bakolitsa, D.Carlton, C.Chen, H.J.Chiu, T.Clayton, M.C.Deller, L.Duan, K.Ellrott, C.L.Farr, J.Feuerhelm, J.C.Grant, A.Grzechnik, G.W.Han, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, P.Kozbial, S.S.Krishna, A.Kumar, W.W.Lam, D.Marciano, D.McMullan, M.D.Miller, A.T.Morse, E.Nigoghossian, A.Nopakun, L.Okach, C.Puckett, R.Reyes, N.Sefcovic, H.J.Tien, C.B.Trame, H.van den Bedem, D.Weekes, T.Wooten, Q.Xu, K.O.Hodgson, J.Wooley, M.A.Elsliger, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2010).
Structures of three members of Pfam PF02663 (FmdE) implicated in microbial methanogenesis reveal a conserved α+β core domain and an auxiliary C-terminal treble-clef zinc finger.
  Acta Crystallogr Sect F Struct Biol Cryst Commun, 66, 1335-1346.
PDB codes: 2glz 2gvi 3d00
  20944231 H.L.Axelrod, P.Kozbial, D.McMullan, S.S.Krishna, M.D.Miller, P.Abdubek, C.Acosta, T.Astakhova, D.Carlton, J.Caruthers, H.J.Chiu, T.Clayton, M.C.Deller, L.Duan, Y.Elias, J.Feuerhelm, S.K.Grzechnik, J.C.Grant, G.W.Han, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, A.Kumar, D.Marciano, A.T.Morse, K.D.Murphy, E.Nigoghossian, L.Okach, S.Oommachen, J.Paulsen, R.Reyes, C.L.Rife, H.J.Tien, C.V.Trout, H.van den Bedem, D.Weekes, A.White, Q.Xu, C.Zubieta, K.O.Hodgson, J.Wooley, M.A.Elsliger, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2010).
Conformational changes associated with the binding of zinc acetate at the putative active site of XcTcmJ, a cupin from Xanthomonas campestris pv. campestris.
  Acta Crystallogr Sect F Struct Biol Cryst Commun, 66, 1347-1353.
PDB code: 3h50
20544237 I.Pérez-Arellano, and J.Cervera (2010).
Glutamate kinase from Thermotoga maritima: characterization of a thermophilic enzyme for proline biosynthesis.
  Extremophiles, 14, 409-415.  
  20944202 M.A.Elsliger, A.M.Deacon, A.Godzik, S.A.Lesley, J.Wooley, K.Wüthrich, and I.A.Wilson (2010).
The JCSG high-throughput structural biology pipeline.
  Acta Crystallogr Sect F Struct Biol Cryst Commun, 66, 1137-1142.  
  20944207 M.D.Miller, L.Aravind, C.Bakolitsa, C.L.Rife, D.Carlton, P.Abdubek, T.Astakhova, H.L.Axelrod, H.J.Chiu, T.Clayton, M.C.Deller, L.Duan, J.Feuerhelm, J.C.Grant, G.W.Han, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, P.Kozbial, S.S.Krishna, A.Kumar, D.Marciano, D.McMullan, A.T.Morse, E.Nigoghossian, L.Okach, R.Reyes, H.van den Bedem, D.Weekes, Q.Xu, K.O.Hodgson, J.Wooley, M.A.Elsliger, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2010).
Structure of the first representative of Pfam family PF04016 (DUF364) reveals enolase and Rossmann-like folds that combine to form a unique active site with a possible role in heavy-metal chelation.
  Acta Crystallogr Sect F Struct Biol Cryst Commun, 66, 1167-1173.
PDB code: 3l5o
21153779 N.Chandra, P.Anand, and K.Yeturu (2010).
Structural bioinformatics: Deriving biological insights from protein structures.
  Interdiscip Sci, 2, 347-366.  
19913036 Q.Xu, A.Bateman, R.D.Finn, P.Abdubek, T.Astakhova, H.L.Axelrod, C.Bakolitsa, D.Carlton, C.Chen, H.J.Chiu, M.Chiu, T.Clayton, D.Das, M.C.Deller, L.Duan, K.Ellrott, D.Ernst, C.L.Farr, J.Feuerhelm, J.C.Grant, A.Grzechnik, G.W.Han, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, P.Kozbial, S.S.Krishna, A.Kumar, D.Marciano, D.McMullan, M.D.Miller, A.T.Morse, E.Nigoghossian, A.Nopakun, L.Okach, C.Puckett, R.Reyes, C.L.Rife, N.Sefcovic, H.J.Tien, C.B.Trame, H.van den Bedem, D.Weekes, T.Wooten, K.O.Hodgson, J.Wooley, M.A.Elsliger, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2010).
Bacterial pleckstrin homology domains: a prokaryotic origin for the PH domain.
  J Mol Biol, 396, 31-46.
PDB codes: 3b77 3dcx 3hsa
  20944216 Q.Xu, D.McMullan, L.Jaroszewski, S.S.Krishna, M.A.Elsliger, A.P.Yeh, P.Abdubek, T.Astakhova, H.L.Axelrod, D.Carlton, H.J.Chiu, T.Clayton, L.Duan, J.Feuerhelm, J.Grant, G.W.Han, K.K.Jin, H.E.Klock, M.W.Knuth, M.D.Miller, A.T.Morse, E.Nigoghossian, L.Okach, S.Oommachen, J.Paulsen, R.Reyes, C.L.Rife, H.van den Bedem, K.O.Hodgson, J.Wooley, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2010).
Structure of an essential bacterial protein YeaZ (TM0874) from Thermotoga maritima at 2.5 Šresolution.
  Acta Crystallogr Sect F Struct Biol Cryst Commun, 66, 1230-1236.
PDB code: 2a6a
  20944223 Q.Xu, P.Abdubek, T.Astakhova, H.L.Axelrod, C.Bakolitsa, X.Cai, D.Carlton, C.Chen, H.J.Chiu, M.Chiu, T.Clayton, D.Das, M.C.Deller, L.Duan, K.Ellrott, C.L.Farr, J.Feuerhelm, J.C.Grant, A.Grzechnik, G.W.Han, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, P.Kozbial, S.S.Krishna, A.Kumar, D.Marciano, D.McMullan, M.D.Miller, A.T.Morse, E.Nigoghossian, A.Nopakun, L.Okach, C.Puckett, R.Reyes, N.Sefcovic, H.J.Tien, C.B.Trame, H.van den Bedem, D.Weekes, T.Wooten, A.Yeh, J.Zhou, K.O.Hodgson, J.Wooley, M.A.Elsliger, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2010).
A conserved fold for fimbrial components revealed by the crystal structure of a putative fimbrial assembly protein (BT1062) from Bacteroides thetaiotaomicron at 2.2 Šresolution.
  Acta Crystallogr Sect F Struct Biol Cryst Commun, 66, 1281-1286.
PDB code: 3gf8
  20944232 Q.Xu, P.Abdubek, T.Astakhova, H.L.Axelrod, C.Bakolitsa, X.Cai, D.Carlton, C.Chen, H.J.Chiu, M.Chiu, T.Clayton, D.Das, M.C.Deller, L.Duan, K.Ellrott, C.L.Farr, J.Feuerhelm, J.C.Grant, A.Grzechnik, G.W.Han, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, P.Kozbial, S.S.Krishna, A.Kumar, W.W.Lam, D.Marciano, M.D.Miller, A.T.Morse, E.Nigoghossian, A.Nopakun, L.Okach, C.Puckett, R.Reyes, H.J.Tien, C.B.Trame, H.van den Bedem, D.Weekes, T.Wooten, A.Yeh, K.O.Hodgson, J.Wooley, M.A.Elsliger, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2010).
Structure of the γ-D-glutamyl-L-diamino acid endopeptidase YkfC from Bacillus cereus in complex with L-Ala-γ-D-Glu: insights into substrate recognition by NlpC/P60 cysteine peptidases.
  Acta Crystallogr Sect F Struct Biol Cryst Commun, 66, 1354-1364.
PDB code: 3h41
  20944225 Q.Xu, P.Abdubek, T.Astakhova, H.L.Axelrod, C.Bakolitsa, X.Cai, D.Carlton, C.Chen, H.J.Chiu, T.Clayton, D.Das, M.C.Deller, L.Duan, K.Ellrott, C.L.Farr, J.Feuerhelm, J.C.Grant, A.Grzechnik, G.W.Han, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, P.Kozbial, S.S.Krishna, A.Kumar, W.W.Lam, D.Marciano, M.D.Miller, A.T.Morse, E.Nigoghossian, A.Nopakun, L.Okach, C.Puckett, R.Reyes, H.J.Tien, C.B.Trame, H.van den Bedem, D.Weekes, T.Wooten, A.Yeh, J.Zhou, K.O.Hodgson, J.Wooley, M.A.Elsliger, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2010).
Structure of a membrane-attack complex/perforin (MACPF) family protein from the human gut symbiont Bacteroides thetaiotaomicron.
  Acta Crystallogr Sect F Struct Biol Cryst Commun, 66, 1297-1305.
PDB code: 3kk7
  20944206 S.S.Krishna, L.Aravind, C.Bakolitsa, J.Caruthers, D.Carlton, M.D.Miller, P.Abdubek, T.Astakhova, H.L.Axelrod, H.J.Chiu, T.Clayton, M.C.Deller, L.Duan, J.Feuerhelm, J.C.Grant, G.W.Han, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, A.Kumar, D.Marciano, D.McMullan, A.T.Morse, E.Nigoghossian, L.Okach, R.Reyes, C.L.Rife, H.van den Bedem, D.Weekes, Q.Xu, K.O.Hodgson, J.Wooley, M.A.Elsliger, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2010).
The structure of SSO2064, the first representative of Pfam family PF01796, reveals a novel two-domain zinc-ribbon OB-fold architecture with a potential acyl-CoA-binding role.
  Acta Crystallogr Sect F Struct Biol Cryst Commun, 66, 1160-1166.
PDB code: 3irb
20399190 Y.Matsumoto, Q.Xu, S.Miyazaki, C.Kaito, C.L.Farr, H.L.Axelrod, H.J.Chiu, H.E.Klock, M.W.Knuth, M.D.Miller, M.A.Elsliger, A.M.Deacon, A.Godzik, S.A.Lesley, K.Sekimizu, and I.A.Wilson (2010).
Structure of a virulence regulatory factor CvfB reveals a novel winged helix RNA binding module.
  Structure, 18, 537-547.
PDB code: 3go5
19364809 C.Kiss, J.Temirov, L.Chasteen, G.S.Waldo, and A.R.Bradbury (2009).
Directed evolution of an extremely stable fluorescent protein.
  Protein Eng Des Sel, 22, 313-323.  
19173316 D.Das, P.Kozbial, H.L.Axelrod, M.D.Miller, D.McMullan, S.S.Krishna, P.Abdubek, C.Acosta, T.Astakhova, P.Burra, D.Carlton, C.Chen, H.J.Chiu, T.Clayton, M.C.Deller, L.Duan, Y.Elias, M.A.Elsliger, D.Ernst, C.Farr, J.Feuerhelm, A.Grzechnik, S.K.Grzechnik, J.Hale, G.W.Han, L.Jaroszewski, K.K.Jin, H.A.Johnson, H.E.Klock, M.W.Knuth, A.Kumar, D.Marciano, A.T.Morse, K.D.Murphy, E.Nigoghossian, A.Nopakun, L.Okach, S.Oommachen, J.Paulsen, C.Puckett, R.Reyes, C.L.Rife, N.Sefcovic, S.Sudek, H.Tien, C.Trame, C.V.Trout, H.van den Bedem, D.Weekes, A.White, Q.Xu, K.O.Hodgson, J.Wooley, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2009).
Crystal structure of a novel Sm-like protein of putative cyanophage origin at 2.60 A resolution.
  Proteins, 75, 296-307.
PDB code: 3by7
19127588 D.Das, S.S.Krishna, D.McMullan, M.D.Miller, Q.Xu, P.Abdubek, C.Acosta, T.Astakhova, H.L.Axelrod, P.Burra, D.Carlton, H.J.Chiu, T.Clayton, M.C.Deller, L.Duan, Y.Elias, M.A.Elsliger, D.Ernst, J.Feuerhelm, A.Grzechnik, S.K.Grzechnik, J.Hale, G.W.Han, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, P.Kozbial, A.Kumar, D.Marciano, A.T.Morse, K.D.Murphy, E.Nigoghossian, L.Okach, S.Oommachen, J.Paulsen, R.Reyes, C.L.Rife, N.Sefcovic, H.Tien, C.B.Trame, C.V.Trout, H.van den Bedem, D.Weekes, A.White, K.O.Hodgson, J.Wooley, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2009).
Crystal structure of the Fic (Filamentation induced by cAMP) family protein SO4266 (gi|24375750) from Shewanella oneidensis MR-1 at 1.6 A resolution.
  Proteins, 75, 264-271.
PDB code: 3eqx
19370033 E.M.Koehn, T.Fleischmann, J.A.Conrad, B.A.Palfey, S.A.Lesley, I.I.Mathews, and A.Kohen (2009).
An unusual mechanism of thymidylate biosynthesis in organisms containing the thyX gene.
  Nature, 458, 919-923.
PDB codes: 3g4a 3g4c
19168617 H.A.Johnson, E.Hampton, and S.A.Lesley (2009).
The Thermotoga maritima Trk potassium transporter--from frameshift to function.
  J Bacteriol, 191, 2276-2284.  
  19949695 H.Dan, A.Balachandran, and M.Lin (2009).
A pair of ligation-independent Escherichia coli expression vectors for rapid addition of a polyhistidine affinity tag to the N- or C-termini of recombinant proteins.
  J Biomol Tech, 20, 241-248.  
19193005 H.S.Lee, G.Spraggon, P.G.Schultz, and F.Wang (2009).
Genetic incorporation of a metal-ion chelating amino acid into proteins as a biophysical probe.
  J Am Chem Soc, 131, 2481-2483.
PDB code: 3fca
18623062 J.G.McCoy, L.J.Bailey, Y.H.Ng, C.A.Bingman, R.Wrobel, A.P.Weber, B.G.Fox, and G.N.Phillips (2009).
Discovery of sarcosine dimethylglycine methyltransferase from Galdieria sulphuraria.
  Proteins, 74, 368-377.  
19425578 L.Columbus, J.Lipfert, K.Jambunathan, D.A.Fox, A.Y.Sim, S.Doniach, and S.A.Lesley (2009).
Mixing and matching detergents for membrane protein NMR structure determination.
  J Am Chem Soc, 131, 7320-7326.  
19370021 M.P.Costi, and S.Ferrari (2009).
Biochemistry: Anchors away.
  Nature, 458, 840-841.  
19307717 M.Zheng, D.R.Cooper, N.E.Grossoehme, M.Yu, L.W.Hung, M.Cieslik, U.Derewenda, S.A.Lesley, I.A.Wilson, D.P.Giedroc, and Z.S.Derewenda (2009).
Structure of Thermotoga maritima TM0439: implications for the mechanism of bacterial GntR transcription regulators with Zn(2+)-binding FCD domains.
  Acta Crystallogr D Biol Crystallogr, 65, 356-365.
PDB code: 3fms
19089981 Q.Xu, C.L.Rife, D.Carlton, M.D.Miller, S.S.Krishna, M.A.Elsliger, P.Abdubek, T.Astakhova, H.J.Chiu, T.Clayton, L.Duan, J.Feuerhelm, S.K.Grzechnik, J.Hale, G.W.Han, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, A.Kumar, D.McMullan, A.T.Morse, E.Nigoghossian, L.Okach, S.Oommachen, J.Paulsen, R.Reyes, H.van den Bedem, K.O.Hodgson, J.Wooley, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2009).
Crystal structure of a novel archaeal AAA+ ATPase SSO1545 from Sulfolobus solfataricus.
  Proteins, 74, 1041-1049.
PDB code: 2fna
19450606 Q.Xu, D.Carlton, M.D.Miller, M.A.Elsliger, S.S.Krishna, P.Abdubek, T.Astakhova, P.Burra, H.J.Chiu, T.Clayton, M.C.Deller, L.Duan, Y.Elias, J.Feuerhelm, J.C.Grant, A.Grzechnik, S.K.Grzechnik, G.W.Han, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, P.Kozbial, A.Kumar, D.Marciano, D.McMullan, A.T.Morse, E.Nigoghossian, L.Okach, S.Oommachen, J.Paulsen, R.Reyes, C.L.Rife, N.Sefcovic, C.Trame, C.V.Trout, H.van den Bedem, D.Weekes, K.O.Hodgson, J.Wooley, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2009).
Crystal structure of histidine phosphotransfer protein ShpA, an essential regulator of stalk biogenesis in Caulobacter crescentus.
  J Mol Biol, 390, 686-698.
PDB code: 2ooc
19000695 Q.Xu, D.McMullan, P.Abdubek, T.Astakhova, D.Carlton, C.Chen, H.J.Chiu, T.Clayton, D.Das, M.C.Deller, L.Duan, M.A.Elsliger, J.Feuerhelm, J.Hale, G.W.Han, L.Jaroszewski, K.K.Jin, H.A.Johnson, H.E.Klock, M.W.Knuth, P.Kozbial, S.Sri Krishna, A.Kumar, D.Marciano, M.D.Miller, A.T.Morse, E.Nigoghossian, A.Nopakun, L.Okach, S.Oommachen, J.Paulsen, C.Puckett, R.Reyes, C.L.Rife, N.Sefcovic, C.Trame, H.van den Bedem, D.Weekes, K.O.Hodgson, J.Wooley, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2009).
A structural basis for the regulatory inactivation of DnaA.
  J Mol Biol, 385, 368-380.
PDB code: 3bos
19217401 Q.Xu, S.Sudek, D.McMullan, M.D.Miller, B.Geierstanger, D.H.Jones, S.S.Krishna, G.Spraggon, B.Bursalay, P.Abdubek, C.Acosta, E.Ambing, T.Astakhova, H.L.Axelrod, D.Carlton, J.Caruthers, H.J.Chiu, T.Clayton, M.C.Deller, L.Duan, Y.Elias, M.A.Elsliger, J.Feuerhelm, S.K.Grzechnik, J.Hale, G.W.Han, J.Haugen, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, P.Kozbial, A.Kumar, D.Marciano, A.T.Morse, E.Nigoghossian, L.Okach, S.Oommachen, J.Paulsen, R.Reyes, C.L.Rife, C.V.Trout, H.van den Bedem, D.Weekes, A.White, G.Wolf, C.Zubieta, K.O.Hodgson, J.Wooley, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2009).
Structural basis of murein peptide specificity of a gamma-D-glutamyl-l-diamino acid endopeptidase.
  Structure, 17, 303-313.
PDB codes: 2evr 2fg0 2hbw
19762644 Y.Zhang, I.Thiele, D.Weekes, Z.Li, L.Jaroszewski, K.Ginalski, A.M.Deacon, J.Wooley, S.A.Lesley, I.A.Wilson, B.Palsson, A.Osterman, and A.Godzik (2009).
Three-dimensional structural view of the central metabolic network of Thermotoga maritima.
  Science, 325, 1544-1549.  
18214971 A.S.Ozyurt, and T.L.Selby (2008).
Computational active site analysis of molecular pathways to improve functional classification of enzymes.
  Proteins, 72, 184-196.  
18054092 B.Canard, J.S.Joseph, and P.Kuhn (2008).
International research networks in viral structural proteomics: again, lessons from SARS.
  Antiviral Res, 78, 47-50.  
19956359 C.A.Smith, and A.E.Cohen (2008).
The Stanford Automated Mounter: Enabling High-Throughput Protein Crystal Screening at SSRL.
  JALA Charlottesv Va, 13, 335-343.  
18369189 C.J.McCleverty, L.Columbus, A.Kreusch, and S.A.Lesley (2008).
Structure and ligand binding of the soluble domain of a Thermotoga maritima membrane protein of unknown function TM1634.
  Protein Sci, 17, 869-877.
PDB codes: 2vkj 2vko
19053285 D.A.Critton, A.Tortajada, G.Stetson, W.Peti, and R.Page (2008).
Structural basis of substrate recognition by hematopoietic tyrosine phosphatase.
  Biochemistry, 47, 13336-13345.
PDB codes: 2hvl 2qdc 2qdm 2qdp 3d42 3d44
18276644 D.A.Rodionov, X.Li, I.A.Rodionova, C.Yang, L.Sorci, E.Dervyn, D.Martynowski, H.Zhang, M.S.Gelfand, and A.L.Osterman (2008).
Transcriptional regulation of NAD metabolism in bacteria: genomic reconstruction of NiaR (YrxA) regulon.
  Nucleic Acids Res, 36, 2032-2046.  
18199319 D.Piedra, S.Lois, and X.de la Cruz (2008).
Preservation of protein clefts in comparative models.
  BMC Struct Biol, 8, 2.  
17563834 F.E.Jenney, and M.W.Adams (2008).
The impact of extremophiles on structural genomics (and vice versa).
  Extremophiles, 12, 39-50.  
19018098 F.J.St John, B.Feng, and E.Pozharski (2008).
The role of bias in crystallization conditions in automated microseeding.
  Acta Crystallogr D Biol Crystallogr, 64, 1222-1227.  
18161025 F.L.Yang, K.F.Hua, Y.L.Yang, W.Zou, Y.P.Chen, S.M.Liang, H.Y.Hsu, and S.H.Wu (2008).
TLR-independent induction of human monocyte IL-1 by phosphoglycolipids from thermophilic bacteria.
  Glycoconj J, 25, 427-439.  
18004753 H.E.Klock, E.J.Koesema, M.W.Knuth, and S.A.Lesley (2008).
Combining the polymerase incomplete primer extension method for cloning and mutagenesis with microscreening to accelerate structural genomics efforts.
  Proteins, 71, 982-994.  
18260100 H.L.Axelrod, D.McMullan, S.S.Krishna, M.D.Miller, M.A.Elsliger, P.Abdubek, E.Ambing, T.Astakhova, D.Carlton, H.J.Chiu, T.Clayton, L.Duan, J.Feuerhelm, S.K.Grzechnik, J.Hale, G.W.Han, J.Haugen, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, E.Koesema, A.T.Morse, E.Nigoghossian, L.Okach, S.Oommachen, J.Paulsen, K.Quijano, R.Reyes, C.L.Rife, H.van den Bedem, D.Weekes, A.White, G.Wolf, Q.Xu, K.O.Hodgson, J.Wooley, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2008).
Crystal structure of AICAR transformylase IMP cyclohydrolase (TM1249) from Thermotoga maritima at 1.88 A resolution.
  Proteins, 71, 1042-1049.
PDB code: 1zcz
18004772 I.I.Mathews, D.McMullan, M.D.Miller, J.M.Canaves, M.A.Elsliger, R.Floyd, S.K.Grzechnik, L.Jaroszewski, H.E.Klock, E.Koesema, J.S.Kovarik, A.Kreusch, P.Kuhn, T.M.McPhillips, A.T.Morse, K.Quijano, C.L.Rife, R.Schwarzenbacher, G.Spraggon, R.C.Stevens, H.van den Bedem, D.Weekes, G.Wolf, K.O.Hodgson, J.Wooley, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2008).
Crystal structure of 2-keto-3-deoxygluconate kinase (TM0067) from Thermotoga maritima at 2.05 A resolution.
  Proteins, 70, 603-608.
PDB code: 2afb
18067292 J.J.Graziano, W.Liu, R.Perera, B.H.Geierstanger, S.A.Lesley, and P.G.Schultz (2008).
Selecting folded proteins from a library of secondary structural elements.
  J Am Chem Soc, 130, 176-185.  
18677553 M.Sugahara, Y.Asada, K.Shimizu, H.Yamamoto, N.K.Lokanath, H.Mizutani, B.Bagautdinov, Y.Matsuura, M.Taketa, Y.Kageyama, N.Ono, Y.Morikawa, Y.Tanaka, H.Shimada, T.Nakamoto, M.Sugahara, M.Yamamoto, and N.Kunishima (2008).
High-throughput crystallization-to-structure pipeline at RIKEN SPring-8 Center.
  J Struct Funct Genomics, 9, 21-28.  
18275810 N.Alexander, M.Bortolus, A.Al-Mestarihi, H.Mchaourab, and J.Meiler (2008).
De novo high-resolution protein structure determination from sparse spin-labeling EPR data.
  Structure, 16, 181-195.  
18324683 P.Kozbial, Q.Xu, H.J.Chiu, D.McMullan, S.S.Krishna, M.D.Miller, P.Abdubek, C.Acosta, T.Astakhova, H.L.Axelrod, D.Carlton, T.Clayton, M.Deller, L.Duan, Y.Elias, M.A.Elsliger, J.Feuerhelm, S.K.Grzechnik, J.Hale, G.W.Han, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, E.Koesema, A.Kumar, D.Marciano, A.T.Morse, K.D.Murphy, E.Nigoghossian, L.Okach, S.Oommachen, R.Reyes, C.L.Rife, G.Spraggon, C.V.Trout, H.van den Bedem, D.Weekes, A.White, G.Wolf, C.Zubieta, K.O.Hodgson, J.Wooley, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2008).
Crystal structures of MW1337R and lin2004: representatives of a novel protein family that adopt a four-helical bundle fold.
  Proteins, 71, 1589-1596.
PDB codes: 2ets 2huj
18275082 Q.Xu, P.Kozbial, D.McMullan, S.S.Krishna, S.M.Brittain, S.B.Ficarro, M.DiDonato, M.D.Miller, P.Abdubek, H.L.Axelrod, H.J.Chiu, T.Clayton, L.Duan, M.A.Elsliger, J.Feuerhelm, S.K.Grzechnik, J.Hale, G.W.Han, L.Jaroszewski, H.E.Klock, A.T.Morse, E.Nigoghossian, J.Paulsen, R.Reyes, C.L.Rife, H.van den Bedem, A.White, K.O.Hodgson, J.Wooley, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2008).
Crystal structure of an ADP-ribosylated protein with a cytidine deaminase-like fold, but unknown function (TM1506), from Thermotoga maritima at 2.70 A resolution.
  Proteins, 71, 1546-1552.
PDB code: 1vk9
19018095 R.Liu, Y.Freund, and G.Spraggon (2008).
Image-based crystal detection: a machine-learning approach.
  Acta Crystallogr D Biol Crystallogr, 64, 1187-1195.  
18094477 R.Schwarzenbacher, A.Godzik, and L.Jaroszewski (2008).
The JCSG MR pipeline: optimized alignments, multiple models and parallel searches.
  Acta Crystallogr D Biol Crystallogr, 64, 133-140.  
18270995 S.Ferrari, V.Losasso, and M.P.Costi (2008).
Sequence-based identification of specific drug target regions in the thymidylate synthase enzyme family.
  ChemMedChem, 3, 392-401.  
18235434 S.Gräslund, P.Nordlund, J.Weigelt, J.Bray, O.Gileadi, S.Knapp, U.Oppermann, C.Arrowsmith, R.Hui, J.Ming, S.dhe-Paganon, H.W.Park, A.Savchenko, A.Yee, A.Edwards, R.Vincentelli, C.Cambillau, R.Kim, S.H.Kim, Z.Rao, Y.Shi, T.C.Terwilliger, C.Y.Kim, L.W.Hung, G.S.Waldo, Y.Peleg, S.Albeck, T.Unger, O.Dym, J.Prilusky, J.L.Sussman, R.C.Stevens, S.A.Lesley, I.A.Wilson, A.Joachimiak, F.Collart, I.Dementieva, M.I.Donnelly, W.H.Eschenfeldt, Y.Kim, L.Stols, R.Wu, M.Zhou, S.K.Burley, J.S.Emtage, J.M.Sauder, D.Thompson, K.Bain, J.Luz, T.Gheyi, F.Zhang, S.Atwell, S.C.Almo, J.B.Bonanno, A.Fiser, S.Swaminathan, F.W.Studier, M.R.Chance, A.Sali, T.B.Acton, R.Xiao, L.Zhao, L.C.Ma, J.F.Hunt, L.Tong, K.Cunningham, M.Inouye, S.Anderson, H.Janjua, R.Shastry, C.K.Ho, D.Wang, H.Wang, M.Jiang, G.T.Montelione, D.I.Stuart, R.J.Owens, S.Daenke, A.Schütz, U.Heinemann, S.Yokoyama, K.Büssow, and K.C.Gunsalus (2008).
Protein production and purification.
  Nat Methods, 5, 135-146.  
19018097 S.M.Soltis, A.E.Cohen, A.Deacon, T.Eriksson, A.González, S.McPhillips, H.Chui, P.Dunten, M.Hollenbeck, I.Mathews, M.Miller, P.Moorhead, R.P.Phizackerley, C.Smith, J.Song, H.van dem Bedem, P.Ellis, P.Kuhn, T.McPhillips, N.Sauter, K.Sharp, I.Tsyba, and G.Wolf (2008).
New paradigm for macromolecular crystallography experiments at SSRL: automated crystal screening and remote data collection.
  Acta Crystallogr D Biol Crystallogr, 64, 1210-1221.  
18988628 Y.C.Chen, and C.Lim (2008).
Common physical basis of macromolecule-binding sites in proteins.
  Nucleic Acids Res, 36, 7078-7087.  
17216455 A.Chernyshev, T.Fleischmann, and A.Kohen (2007).
Thymidyl biosynthesis enzymes as antibiotic targets.
  Appl Microbiol Biotechnol, 74, 282-289.  
17609801 A.Chernyshev, T.Fleischmann, E.M.Koehn, S.A.Lesley, and A.Kohen (2007).
The relationships between oxidase and synthase activities of flavin dependent thymidylate synthase (FDTS).
  Chem Commun (Camb), (), 2861-2863.  
17553160 A.Ergin, K.Büssow, J.Sieper, A.Thiel, R.Duchmann, and T.Adam (2007).
Homologous high-throughput expression and purification of highly conserved E coli proteins.
  Microb Cell Fact, 6, 18.  
17091222 C.Labarre, H.van Tilbeurgh, and K.Blondeau (2007).
Pichia pastoris is a valuable host for the expression of genes encoding membrane proteins from the hyperthermophilic Archeon Pyrococcus abyssi.
  Extremophiles, 11, 403-413.  
17546672 C.Zubieta, S.S.Krishna, D.McMullan, M.D.Miller, P.Abdubek, S.Agarwalla, E.Ambing, T.Astakhova, H.L.Axelrod, D.Carlton, H.J.Chiu, T.Clayton, M.Deller, M.DiDonato, L.Duan, M.A.Elsliger, S.K.Grzechnik, J.Hale, E.Hampton, G.W.Han, J.Haugen, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, E.Koesema, A.Kumar, D.Marciano, A.T.Morse, E.Nigoghossian, S.Oommachen, R.Reyes, C.L.Rife, H.van den Bedem, D.Weekes, A.White, Q.Xu, K.O.Hodgson, J.Wooley, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2007).
Crystal structure of homoserine O-succinyltransferase from Bacillus cereus at 2.4 A resolution.
  Proteins, 68, 999.
PDB code: 2ghr
17654545 C.Zubieta, S.S.Krishna, M.Kapoor, P.Kozbial, D.McMullan, H.L.Axelrod, M.D.Miller, P.Abdubek, E.Ambing, T.Astakhova, D.Carlton, H.J.Chiu, T.Clayton, M.C.Deller, L.Duan, M.A.Elsliger, J.Feuerhelm, S.K.Grzechnik, J.Hale, E.Hampton, G.W.Han, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, A.Kumar, D.Marciano, A.T.Morse, E.Nigoghossian, L.Okach, S.Oommachen, R.Reyes, C.L.Rife, P.Schimmel, H.van den Bedem, D.Weekes, A.White, Q.Xu, K.O.Hodgson, J.Wooley, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2007).
Crystal structures of two novel dye-decolorizing peroxidases reveal a beta-barrel fold with a conserved heme-binding motif.
  Proteins, 69, 223-233.
PDB codes: 2gvk 2hag
17256761 D.Weekes, M.D.Miller, S.S.Krishna, D.McMullan, T.M.McPhillips, C.Acosta, J.M.Canaves, M.A.Elsliger, R.Floyd, S.K.Grzechnik, L.Jaroszewski, H.E.Klock, E.Koesema, J.S.Kovarik, A.Kreusch, A.T.Morse, K.Quijano, G.Spraggon, H.van den Bedem, G.Wolf, K.O.Hodgson, J.Wooley, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2007).
Crystal structure of a transcription regulator (TM1602) from Thermotoga maritima at 2.3 A resolution.
  Proteins, 67, 247-252.
PDB code: 1j5y
17242505 E.Brostromer, J.Nan, and X.D.Su (2007).
An automated image-collection system for crystallization experiments using SBS standard microplates.
  Acta Crystallogr D Biol Crystallogr, 63, 119-125.  
17444523 L.Premkumar, C.L.Rife, S.Sri Krishna, D.McMullan, M.D.Miller, P.Abdubek, E.Ambing, T.Astakhova, H.L.Axelrod, J.M.Canaves, D.Carlton, H.J.Chiu, T.Clayton, M.DiDonato, L.Duan, M.A.Elsliger, J.Feuerhelm, R.Floyd, S.K.Grzechnik, J.Hale, E.Hampton, G.W.Han, J.Haugen, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, E.Koesema, J.S.Kovarik, A.Kreusch, I.Levin, T.M.McPhillips, A.T.Morse, E.Nigoghossian, L.Okach, S.Oommachen, J.Paulsen, K.Quijano, R.Reyes, F.Rezezadeh, D.Rodionov, R.Schwarzenbacher, G.Spraggon, H.van den Bedem, A.White, G.Wolf, Q.Xu, K.O.Hodgson, J.Wooley, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2007).
Crystal structure of TM1030 from Thermotoga maritima at 2.3 A resolution reveals molecular details of its transcription repressor function.
  Proteins, 68, 418-424.
PDB code: 1zkg
17962404 L.Slabinski, L.Jaroszewski, A.P.Rodrigues, L.Rychlewski, I.A.Wilson, S.A.Lesley, and A.Godzik (2007).
The challenge of protein structure determination--lessons from structural genomics.
  Protein Sci, 16, 2472-2482.  
17078969 M.A.White, K.M.Clark, E.J.Grayhack, and M.E.Dumont (2007).
Characteristics affecting expression and solubilization of yeast membrane proteins.
  J Mol Biol, 365, 621-636.  
  19005562 M.D.Miller, and A.M.Deacon (2007).
An X-ray microsource based system for crystal screening and beamline development during synchrotron shutdown periods.
  Nucl Instrum Methods Phys Res A, 582, 233-235.  
17154423 N.Mirkovic, Z.Li, A.Parnassa, and D.Murray (2007).
Strategies for high-throughput comparative modeling: applications to leverage analysis in structural genomics and protein family organization.
  Proteins, 66, 766-777.  
17616525 P.P.Chamberlain, X.Qian, A.R.Stiles, J.Cho, D.H.Jones, S.A.Lesley, E.A.Grabau, S.B.Shears, and G.Spraggon (2007).
Integration of inositol phosphate signaling pathways via human ITPK1.
  J Biol Chem, 282, 28117-28125.
PDB codes: 2q7d 2qb5
17654724 Q.Xu, K.S.Saikatendu, S.S.Krishna, D.McMullan, P.Abdubek, S.Agarwalla, E.Ambing, T.Astakhova, H.L.Axelrod, D.Carlton, H.J.Chiu, T.Clayton, M.DiDonato, L.Duan, M.A.Elsliger, J.Feuerhelm, S.K.Grzechnik, J.Hale, E.Hampton, G.W.Han, J.Haugen, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, E.Koesema, M.D.Miller, A.T.Morse, E.Nigoghossian, L.Okach, S.Oommachen, J.Paulsen, R.Reyes, C.L.Rife, R.Schwarzenbacher, H.van den Bedem, A.White, G.Wolf, K.O.Hodgson, J.Wooley, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2007).
Crystal structure of MtnX phosphatase from Bacillus subtilis at 2.0 A resolution provides a structural basis for bipartite phosphomonoester hydrolysis of 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate.
  Proteins, 69, 433-439.
PDB code: 2fea
17636569 S.S.Krishna, L.Tautz, Q.Xu, D.McMullan, M.D.Miller, P.Abdubek, E.Ambing, T.Astakhova, H.L.Axelrod, D.Carlton, H.J.Chiu, T.Clayton, M.DiDonato, L.Duan, M.A.Elsliger, S.K.Grzechnik, J.Hale, E.Hampton, G.W.Han, J.Haugen, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, E.Koesema, A.T.Morse, T.Mustelin, E.Nigoghossian, S.Oommachen, R.Reyes, C.L.Rife, H.van den Bedem, D.Weekes, A.White, K.O.Hodgson, J.Wooley, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2007).
Crystal structure of NMA1982 from Neisseria meningitidis at 1.5 A resolution provides a structural scaffold for nonclassical, eukaryotic-like phosphatases.
  Proteins, 69, 415-421.
PDB code: 2f46
17492715 T.Alm, J.Steen, J.Ottosson, and S.Hober (2007).
High-throughput protein purification under denaturating conditions by the use of cation exchange chromatography.
  Biotechnol J, 2, 709-716.  
16381863 C.Guda, L.R.Pal, and I.N.Shindyalov (2006).
DMAPS: a database of multiple alignments for protein structures.
  Nucleic Acids Res, 34, D273-D276.  
16882997 C.J.McCleverty, E.Koesema, A.Patapoutian, S.A.Lesley, and A.Kreusch (2006).
Crystal structure of the human TRPV2 channel ankyrin repeat domain.
  Protein Sci, 15, 2201-2206.
PDB code: 2f37
17132859 G.A.Malawski, R.C.Hillig, F.Monteclaro, U.Eberspaecher, A.A.Schmitz, K.Crusius, M.Huber, U.Egner, P.Donner, and B.Müller-Tiemann (2006).
Identifying protein construct variants with increased crystallization propensity--a case study.
  Protein Sci, 15, 2718-2728.  
16779835 G.W.Han, S.Sri Krishna, R.Schwarzenbacher, D.McMullan, K.Ginalski, M.A.Elsliger, S.M.Brittain, P.Abdubek, S.Agarwalla, E.Ambing, T.Astakhova, H.Axelrod, J.M.Canaves, H.J.Chiu, M.DiDonato, S.K.Grzechnik, J.Hale, E.Hampton, J.Haugen, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, E.Koesema, A.Kreusch, P.Kuhn, M.D.Miller, A.T.Morse, K.Moy, E.Nigoghossian, S.Oommachen, J.Ouyang, J.Paulsen, K.Quijano, R.Reyes, C.Rife, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, X.Wang, B.West, A.White, G.Wolf, Q.Xu, K.O.Hodgson, J.Wooley, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2006).
Crystal structure of the ApbE protein (TM1553) from Thermotoga maritima at 1.58 A resolution.
  Proteins, 64, 1083-1090.
PDB code: 1vrm
16865708 I.I.Mathews, S.S.Krishna, R.Schwarzenbacher, D.McMullan, L.Jaroszewski, M.D.Miller, P.Abdubek, S.Agarwalla, E.Ambing, H.L.Axelrod, J.M.Canaves, D.Carlton, H.J.Chiu, T.Clayton, M.DiDonato, L.Duan, M.A.Elsliger, S.K.Grzechnik, J.Hale, E.Hampton, J.Haugen, K.K.Jin, H.E.Klock, E.Koesema, J.S.Kovarik, A.Kreusch, P.Kuhn, I.Levin, A.T.Morse, E.Nigoghossian, L.Okach, S.Oommachen, J.Paulsen, K.Quijano, R.Reyes, C.L.Rife, G.Spraggon, R.C.Stevens, H.van den Bedem, A.White, G.Wolf, Q.Xu, K.O.Hodgson, J.Wooley, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2006).
Crystal structure of phosphoribosylformyl-glycinamidine synthase II, PurS subunit (TM1244) from Thermotoga maritima at 1.90 A resolution.
  Proteins, 65, 249-254.
PDB code: 1vq3
16544324 I.I.Mathews, S.S.Krishna, R.Schwarzenbacher, D.McMullan, P.Abdubek, E.Ambing, J.M.Canaves, H.J.Chiu, A.M.Deacon, M.DiDonato, M.A.Elsliger, A.Godzik, C.Grittini, S.K.Grzechnik, J.Hale, E.Hampton, G.W.Han, J.Haugen, L.Jaroszewski, H.E.Klock, E.Koesema, A.Kreusch, P.Kuhn, S.A.Lesley, I.Levin, M.D.Miller, K.Moy, E.Nigoghossian, J.Paulsen, K.Quijano, R.Reyes, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, A.White, G.Wolf, Q.Xu, K.O.Hodgson, J.Wooley, and I.A.Wilson (2006).
Crystal structure of phosphoribosylformylglycinamidine synthase II (smPurL) from Thermotoga maritima at 2.15 A resolution.
  Proteins, 63, 1106-1111.
PDB code: 1vk3
17001091 I.M.Berry, O.Dym, R.M.Esnouf, K.Harlos, R.Meged, A.Perrakis, J.L.Sussman, T.S.Walter, J.Wilson, and A.Messerschmidt (2006).
SPINE high-throughput crystallization, crystal imaging and recognition techniques: current state, performance analysis, new technologies and future aspects.
  Acta Crystallogr D Biol Crystallogr, 62, 1137-1149.  
16544291 K.K.Jin, S.S.Krishna, R.Schwarzenbacher, D.McMullan, P.Abdubek, S.Agarwalla, E.Ambing, H.Axelrod, J.M.Canaves, H.J.Chiu, A.M.Deacon, M.DiDonato, M.A.Elsliger, J.Feuerhelm, A.Godzik, C.Grittini, S.K.Grzechnik, J.Hale, E.Hampton, J.Haugen, M.Hornsby, L.Jaroszewski, H.E.Klock, M.W.Knuth, E.Koesema, A.Kreusch, P.Kuhn, S.A.Lesley, M.D.Miller, K.Moy, E.Nigoghossian, L.Okach, S.Oommachen, J.Paulsen, K.Quijano, R.Reyes, C.Rife, R.C.Stevens, G.Spraggon, H.van den Bedem, J.Velasquez, A.White, G.Wolf, G.W.Han, Q.Xu, K.O.Hodgson, J.Wooley, and I.A.Wilson (2006).
Crystal structure of TM1367 from Thermotoga maritima at 1.90 A resolution reveals an atypical member of the cyclophilin (peptidylprolyl isomerase) fold.
  Proteins, 63, 1112-1118.
PDB code: 1zx8
16597824 L.Columbus, J.Lipfert, H.Klock, I.Millett, S.Doniach, and S.A.Lesley (2006).
Expression, purification, and characterization of Thermotoga maritima membrane proteins for structure determination.
  Protein Sci, 15, 961-975.  
16597827 M.A.Johnson, W.Peti, T.Herrmann, I.A.Wilson, and K.Wüthrich (2006).
Solution structure of Asl1650, an acyl carrier protein from Anabaena sp. PCC 7120 with a variant phosphopantetheinylation-site sequence.
  Protein Sci, 15, 1030-1041.
PDB codes: 2afd 2afe
16435371 M.DiDonato, S.S.Krishna, R.Schwarzenbacher, D.McMullan, L.Jaroszewski, M.D.Miller, P.Abdubek, S.Agarwalla, E.Ambing, H.Axelrod, T.Biorac, H.J.Chiu, A.M.Deacon, M.A.Elsliger, J.Feuerhelm, A.Godzik, C.Grittini, S.K.Grzechnik, J.Hale, E.Hampton, J.Haugen, M.Hornsby, H.E.Klock, M.W.Knuth, E.Koesema, A.Kreusch, P.Kuhn, S.A.Lesley, K.Moy, E.Nigoghossian, L.Okach, J.Paulsen, K.Quijano, R.Reyes, C.Rife, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, A.White, G.Wolf, Q.Xu, K.O.Hodgson, J.Wooley, and I.A.Wilson (2006).
Crystal structure of a single-stranded DNA-binding protein (TM0604) from Thermotoga maritima at 2.60 A resolution.
  Proteins, 63, 256-260.
PDB code: 1z9f
16927339 M.DiDonato, S.S.Krishna, R.Schwarzenbacher, D.McMullan, S.Agarwalla, S.M.Brittain, M.D.Miller, P.Abdubek, E.Ambing, H.L.Axelrod, J.M.Canaves, H.J.Chiu, A.M.Deacon, L.Duan, M.A.Elsliger, A.Godzik, S.K.Grzechnik, J.Hale, E.Hampton, J.Haugen, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, E.Koesema, A.Kreusch, P.Kuhn, S.A.Lesley, I.Levin, A.T.Morse, E.Nigoghossian, L.Okach, S.Oommachen, J.Paulsen, K.Quijano, R.Reyes, C.L.Rife, G.Spraggon, R.C.Stevens, H.van den Bedem, A.White, G.Wolf, Q.Xu, K.O.Hodgson, J.Wooley, and I.A.Wilson (2006).
Crystal structure of 2-phosphosulfolactate phosphatase (ComB) from Clostridium acetobutylicum at 2.6 A resolution reveals a new fold with a novel active site.
  Proteins, 65, 771-776.
PDB code: 1vr0
16850178 M.Hammarström, E.A.Woestenenk, N.Hellgren, T.Härd, and H.Berglund (2006).
Effect of N-terminal solubility enhancing fusion proteins on yield of purified target protein.
  J Struct Funct Genomics, 7, 1.  
16988933 M.Kosloff, G.W.Han, S.S.Krishna, R.Schwarzenbacher, M.Fasnacht, M.A.Elsliger, P.Abdubek, S.Agarwalla, E.Ambing, T.Astakhova, H.L.Axelrod, J.M.Canaves, D.Carlton, H.J.Chiu, T.Clayton, M.DiDonato, L.Duan, J.Feuerhelm, C.Grittini, S.K.Grzechnik, J.Hale, E.Hampton, J.Haugen, L.Jaroszewski, K.K.Jin, H.Johnson, H.E.Klock, M.W.Knuth, E.Koesema, A.Kreusch, P.Kuhn, I.Levin, D.McMullan, M.D.Miller, A.T.Morse, K.Moy, E.Nigoghossian, L.Okach, S.Oommachen, R.Page, J.Paulsen, K.Quijano, R.Reyes, C.L.Rife, E.Sims, G.Spraggon, V.Sridhar, R.C.Stevens, H.van den Bedem, J.Velasquez, A.White, G.Wolf, Q.Xu, K.O.Hodgson, J.Wooley, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2006).
Comparative structural analysis of a novel glutathioneS-transferase (ATU5508) from Agrobacterium tumefaciens at 2.0 A resolution.
  Proteins, 65, 527-537.
PDB code: 2fno
16475229 N.P.Cowieson, B.Wensley, P.Listwan, D.A.Hume, B.Kobe, and J.L.Martin (2006).
An automatable screen for the rapid identification of proteins amenable to refolding.
  Proteomics, 6, 1750-1757.  
17001088 P.M.Alzari, H.Berglund, N.S.Berrow, E.Blagova, D.Busso, C.Cambillau, V.Campanacci, E.Christodoulou, S.Eiler, M.J.Fogg, G.Folkers, A.Geerlof, D.Hart, A.Haouz, M.D.Herman, S.Macieira, P.Nordlund, A.Perrakis, S.Quevillon-Cheruel, F.Tarandeau, H.van Tilbeurgh, T.Unger, M.P.Luna-Vargas, M.Velarde, M.Willmanns, and R.J.Owens (2006).
Implementation of semi-automated cloning and prokaryotic expression screening: the impact of SPINE.
  Acta Crystallogr D Biol Crystallogr, 62, 1103-1113.  
16287129 Q.Xu, R.Schwarzenbacher, D.McMullan, P.Abdubek, S.Agarwalla, E.Ambing, H.Axelrod, T.Biorac, J.M.Canaves, H.J.Chiu, A.M.Deacon, M.DiDonato, M.A.Elsliger, A.Godzik, C.Grittini, S.K.Grzechnik, J.Hale, E.Hampton, G.W.Han, J.Haugen, M.Hornsby, L.Jaroszewski, H.E.Klock, E.Koesema, A.Kreusch, P.Kuhn, S.A.Lesley, M.D.Miller, K.Moy, E.Nigoghossian, J.Paulsen, K.Quijano, R.Reyes, C.Rife, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, A.White, G.Wolf, K.O.Hodgson, J.Wooley, and I.A.Wilson (2006).
Crystal structure of virulence factor CJ0248 from Campylobacter jejuni at 2.25 A resolution reveals a new fold.
  Proteins, 62, 292-296.
PDB code: 1vqr
16783794 Q.Xu, R.Schwarzenbacher, S.S.Krishna, D.McMullan, S.Agarwalla, K.Quijano, P.Abdubek, E.Ambing, H.Axelrod, T.Biorac, J.M.Canaves, H.J.Chiu, M.A.Elsliger, C.Grittini, S.K.Grzechnik, M.DiDonato, J.Hale, E.Hampton, G.W.Han, J.Haugen, M.Hornsby, L.Jaroszewski, H.E.Klock, M.W.Knuth, E.Koesema, A.Kreusch, P.Kuhn, M.D.Miller, K.Moy, E.Nigoghossian, J.Paulsen, R.Reyes, C.Rife, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, A.White, G.Wolf, K.O.Hodgson, J.Wooley, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2006).
Crystal structure of acireductone dioxygenase (ARD) from Mus musculus at 2.06 angstrom resolution.
  Proteins, 64, 808-813.
PDB code: 1vr3
16948158 Q.Xu, S.S.Krishna, D.McMullan, R.Schwarzenbacher, M.D.Miller, P.Abdubek, S.Agarwalla, E.Ambing, T.Astakhova, H.L.Axelrod, J.M.Canaves, D.Carlton, H.J.Chiu, T.Clayton, M.DiDonato, L.Duan, M.A.Elsliger, J.Feuerhelm, S.K.Grzechnik, J.Hale, E.Hampton, G.W.Han, J.Haugen, L.Jaroszewski, K.K.Jin, H.E.Klock, M.W.Knuth, E.Koesema, A.Kreusch, P.Kuhn, A.T.Morse, E.Nigoghossian, L.Okach, S.Oommachen, J.Paulsen, K.Quijano, R.Reyes, C.L.Rife, G.Spraggon, R.C.Stevens, H.van den Bedem, A.White, G.Wolf, K.O.Hodgson, J.Wooley, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2006).
Crystal structure of an ORFan protein (TM1622) from Thermotoga maritima at 1.75 A resolution reveals a fold similar to the Ran-binding protein Mog1p.
  Proteins, 65, 777-782.
PDB code: 1vr8
16615077 R.R.Sotelo-Mundo, L.Changchien, F.Maley, and W.R.Montfort (2006).
Crystal structures of thymidylate synthase mutant R166Q: structural basis for the nearly complete loss of catalytic activity.
  J Biochem Mol Toxicol, 20, 88-92.
PDB codes: 1ffl 1fwm
16865707 R.Schwarzenbacher, D.McMullan, S.S.Krishna, Q.Xu, M.D.Miller, J.M.Canaves, M.A.Elsliger, R.Floyd, S.K.Grzechnik, L.Jaroszewski, H.E.Klock, E.Koesema, J.S.Kovarik, A.Kreusch, P.Kuhn, T.M.McPhillips, A.T.Morse, K.Quijano, G.Spraggon, R.C.Stevens, H.van den Bedem, G.Wolf, K.O.Hodgson, J.Wooley, A.M.Deacon, A.Godzik, S.A.Lesley, and I.A.Wilson (2006).
Crystal structure of a glycerate kinase (TM1585) from Thermotoga maritima at 2.70 A resolution reveals a new fold.
  Proteins, 65, 243-248.
PDB code: 2b8n
17064285 S.B.Conners, E.F.Mongodin, M.R.Johnson, C.I.Montero, K.E.Nelson, and R.M.Kelly (2006).
Microbial biochemistry, physiology, and biotechnology of hyperthermophilic Thermotoga species.
  FEMS Microbiol Rev, 30, 872-905.  
16943447 S.Surade, M.Klein, P.C.Stolt-Bergner, C.Muenke, A.Roy, and H.Michel (2006).
Comparative analysis and "expression space" coverage of the production of prokaryotic membrane proteins for structural genomics.
  Protein Sci, 15, 2178-2189.  
17098187 T.S.Walter, C.Meier, R.Assenberg, K.F.Au, J.Ren, A.Verma, J.E.Nettleship, R.J.Owens, D.I.Stuart, and J.M.Grimes (2006).
Lysine methylation as a routine rescue strategy for protein crystallization.
  Structure, 14, 1617-1622.  
16510972 X.Vernede, B.Lavault, J.Ohana, D.Nurizzo, J.Joly, L.Jacquamet, F.Felisaz, F.Cipriani, and D.Bourgeois (2006).
UV laser-excited fluorescence as a tool for the visualization of protein crystals mounted in loops.
  Acta Crystallogr D Biol Crystallogr, 62, 253-261.
PDB codes: 2c8o 2c8p 2c8q 2c8r
16381864 Z.Li, Y.Ye, and A.Godzik (2006).
Flexible Structural Neighborhood--a database of protein structural similarities and alignments.
  Nucleic Acids Res, 34, D277-D280.  
15681862 A.K.Shah, Z.J.Liu, P.D.Stewart, F.D.Schubot, J.P.Rose, M.G.Newton, and B.C.Wang (2005).
On increasing protein-crystallization throughput for X-ray diffraction studies.
  Acta Crystallogr D Biol Crystallogr, 61, 123-129.  
  16511228 B.Collins, R.C.Stevens, and R.Page (2005).
Crystallization Optimum Solubility Screening: using crystallization results to identify the optimal buffer for protein crystal formation.
  Acta Crystallogr Sect F Struct Biol Cryst Commun, 61, 1035-1038.  
15698562 C.J.Mayo, J.M.Diprose, T.S.Walter, I.M.Berry, J.Wilson, R.J.Owens, E.Y.Jones, K.Harlos, D.I.Stuart, and R.M.Esnouf (2005).
Benefits of automated crystallization plate tracking, imaging, and analysis.
  Structure, 13, 175-182.  
16104018 C.Rife, R.Schwarzenbacher, D.McMullan, P.Abdubek, E.Ambing, H.Axelrod, T.Biorac, J.M.Canaves, H.J.Chiu, A.M.Deacon, M.DiDonato, M.A.Elsliger, A.Godzik, C.Grittini, S.K.Grzechnik, J.Hale, E.Hampton, G.W.Han, J.Haugen, M.Hornsby, L.Jaroszewski, H.E.Klock, E.Koesema, A.Kreusch, P.Kuhn, S.A.Lesley, M.D.Miller, K.Moy, E.Nigoghossian, J.Paulsen, K.Quijano, R.Reyes, E.Sims, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, A.White, G.Wolf, Q.Xu, K.O.Hodgson, J.Wooley, and I.A.Wilson (2005).
Crystal structure of the global regulatory protein CsrA from Pseudomonas putida at 2.05 A resolution reveals a new fold.
  Proteins, 61, 449-453.
PDB code: 1vpz
16104019 C.Rife, R.Schwarzenbacher, D.McMullan, P.Abdubek, E.Ambing, H.Axelrod, T.Biorac, J.M.Canaves, H.J.Chiu, A.M.Deacon, M.DiDonato, M.A.Elsliger, A.Godzik, C.Grittini, S.K.Grzechnik, J.Hale, E.Hampton, G.W.Han, J.Haugen, M.Hornsby, L.Jaroszewski, H.E.Klock, E.Koesema, A.Kreusch, P.Kuhn, S.A.Lesley, M.D.Miller, K.Moy, E.Nigoghossian, J.Paulsen, K.Quijano, R.Reyes, E.Sims, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, A.White, G.Wolf, Q.Xu, K.O.Hodgson, J.Wooley, and I.A.Wilson (2005).
Crystal structure of a putative modulator of DNA gyrase (pmbA) from Thermotoga maritima at 1.95 A resolution reveals a new fold.
  Proteins, 61, 444-448.
PDB code: 1vl4
16211510 D.McMullan, J.M.Canaves, K.Quijano, P.Abdubek, E.Nigoghossian, J.Haugen, H.E.Klock, J.Vincent, J.Hale, J.Paulsen, and S.A.Lesley (2005).
High-throughput protein production for X-ray crystallography and use of size exclusion chromatography to validate or refute computational biological unit predictions.
  J Struct Funct Genomics, 6, 135-141.  
16001405 G.W.Han, R.Schwarzenbacher, D.McMullan, P.Abdubek, E.Ambing, H.Axelrod, T.Biorac, J.M.Canaves, H.J.Chiu, X.Dai, A.M.Deacon, M.DiDonato, M.A.Elsliger, A.Godzik, C.Grittini, S.K.Grzechnik, J.Hale, E.Hampton, J.Haugen, M.Hornsby, L.Jaroszewski, H.E.Klock, E.Koesema, A.Kreusch, P.Kuhn, S.A.Lesley, T.M.McPhillips, M.D.Miller, K.Moy, E.Nigoghossian, J.Paulsen, K.Quijano, R.Reyes, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, A.White, G.Wolf, Q.Xu, K.O.Hodgson, J.Wooley, and I.A.Wilson (2005).
Crystal structure of an Apo mRNA decapping enzyme (DcpS) from Mouse at 1.83 A resolution.
  Proteins, 60, 797-802.
PDB code: 1vlr
15657930 G.W.Han, R.Schwarzenbacher, R.Page, L.Jaroszewski, P.Abdubek, E.Ambing, T.Biorac, J.M.Canaves, H.J.Chiu, X.Dai, A.M.Deacon, M.DiDonato, M.A.Elsliger, A.Godzik, C.Grittini, S.K.Grzechnik, J.Hale, E.Hampton, J.Haugen, M.Hornsby, H.E.Klock, E.Koesema, A.Kreusch, P.Kuhn, S.A.Lesley, I.Levin, D.McMullan, T.M.McPhillips, M.D.Miller, A.Morse, K.Moy, E.Nigoghossian, J.Ouyang, J.Paulsen, K.Quijano, R.Reyes, E.Sims, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, F.von Delft, X.Wang, B.West, A.White, G.Wolf, Q.Xu, O.Zagnitko, K.O.Hodgson, J.Wooley, and I.A.Wilson (2005).
Crystal structure of an alanine-glyoxylate aminotransferase from Anabaena sp. at 1.70 A resolution reveals a noncovalently linked PLP cofactor.
  Proteins, 58, 971-975.
PDB code: 1vjo
16211504 H.E.Klock, A.White, E.Koesema, and S.A.Lesley (2005).
Methods and results for semi-automated cloning using integrated robotics.
  J Struct Funct Genomics, 6, 89-94.  
16224779 H.E.Klock, R.Schwarzenbacher, Q.Xu, D.McMullan, P.Abdubek, E.Ambing, H.Axelrod, T.Biorac, J.M.Canaves, H.J.Chiu, A.M.Deacon, M.DiDonato, M.A.Elsliger, A.Godzik, C.Grittini, S.K.Grzechnik, J.Hale, E.Hampton, G.W.Han, J.Haugen, M.Hornsby, L.Jaroszewski, E.Koesema, A.Kreusch, P.Kuhn, M.D.Miller, K.Moy, E.Nigoghossian, J.Paulsen, K.Quijano, R.Reyes, C.Rife, E.Sims, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, A.White, G.Wolf, K.O.Hodgson, J.Wooley, S.A.Lesley, and I.A.Wilson (2005).
Crystal structure of a conserved hypothetical protein (gi: 13879369) from Mouse at 1.90 A resolution reveals a new fold.
  Proteins, 61, 1132-1136.
PDB code: 1vkb
15608370 H.van den Bedem, I.Lotan, J.C.Latombe, and A.M.Deacon (2005).
Real-space protein-model completion: an inverse-kinematics approach.
  Acta Crystallogr D Biol Crystallogr, 61, 2.  
15822122 I.Levin, M.D.Miller, R.Schwarzenbacher, D.McMullan, P.Abdubek, E.Ambing, T.Biorac, J.Cambell, J.M.Canaves, H.J.Chiu, A.M.Deacon, M.DiDonato, M.A.Elsliger, A.Godzik, C.Grittini, S.K.Grzechnik, J.Hale, E.Hampton, G.W.Han, J.Haugen, M.Hornsby, L.Jaroszewski, C.Karlak, H.E.Klock, E.Koesema, A.Kreusch, P.Kuhn, S.A.Lesley, A.Morse, K.Moy, E.Nigoghossian, J.Ouyang, R.Page, K.Quijano, R.Reyes, A.Robb, E.Sims, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, X.Wang, B.West, G.Wolf, Q.Xu, O.Zagnitko, K.O.Hodgson, J.Wooley, and I.A.Wilson (2005).
Crystal structure of an indigoidine synthase A (IndA)-like protein (TM1464) from Thermotoga maritima at 1.90 A resolution reveals a new fold.
  Proteins, 59, 864-868.
PDB code: 1vkm
15822125 I.Mathews, R.Schwarzenbacher, D.McMullan, P.Abdubek, E.Ambing, H.Axelrod, T.Biorac, J.M.Canaves, H.J.Chiu, A.M.Deacon, M.DiDonato, M.A.Elsliger, A.Godzik, C.Grittini, S.K.Grzechnik, J.Hale, E.Hampton, G.W.Han, J.Haugen, M.Hornsby, L.Jaroszewski, H.E.Klock, E.Koesema, A.Kreusch, P.Kuhn, S.A.Lesley, I.Levin, M.D.Miller, K.Moy, E.Nigoghossian, J.Ouyang, J.Paulsen, K.Quijano, R.Reyes, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, A.White, G.Wolf, Q.Xu, K.O.Hodgson, J.Wooley, and I.A.Wilson (2005).
Crystal structure of S-adenosylmethionine:tRNA ribosyltransferase-isomerase (QueA) from Thermotoga maritima at 2.0 A resolution reveals a new fold.
  Proteins, 59, 869-874.
PDB code: 1vky
16154095 J.S.Chappie, J.M.Cànaves, G.W.Han, C.L.Rife, Q.Xu, and R.C.Stevens (2005).
The structure of a eukaryotic nicotinic acid phosphoribosyltransferase reveals structural heterogeneity among type II PRTases.
  Structure, 13, 1385-1396.
PDB code: 1vlp
15624212 J.W.Arndt, R.Schwarzenbacher, R.Page, P.Abdubek, E.Ambing, T.Biorac, J.M.Canaves, H.J.Chiu, X.Dai, A.M.Deacon, M.DiDonato, M.A.Elsliger, A.Godzik, C.Grittini, S.K.Grzechnik, J.Hale, E.Hampton, G.W.Han, J.Haugen, M.Hornsby, H.E.Klock, E.Koesema, A.Kreusch, P.Kuhn, L.Jaroszewski, S.A.Lesley, I.Levin, D.McMullan, T.M.McPhillips, M.D.Miller, A.Morse, K.Moy, E.Nigoghossian, J.Ouyang, W.S.Peti, K.Quijano, R.Reyes, E.Sims, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, F.von Delft, X.Wang, B.West, A.White, G.Wolf, Q.Xu, O.Zagnitko, K.O.Hodgson, J.Wooley, and I.A.Wilson (2005).
Crystal structure of an alpha/beta serine hydrolase (YDR428C) from Saccharomyces cerevisiae at 1.85 A resolution.
  Proteins, 58, 755-758.
PDB code: 1vkh
16271890 K.S.Saikatendu, J.S.Joseph, V.Subramanian, T.Clayton, M.Griffith, K.Moy, J.Velasquez, B.W.Neuman, M.J.Buchmeier, R.C.Stevens, and P.Kuhn (2005).
Structural basis of severe acute respiratory syndrome coronavirus ADP-ribose-1''-phosphate dephosphorylation by a conserved domain of nsP3.
  Structure, 13, 1665-1675.
PDB code: 2acf
15937903 L.Columbus, W.Peti, T.Etezady-Esfarjani, T.Herrmann, and K.Wüthrich (2005).
NMR structure determination of the conserved hypothetical protein TM1816 from Thermotoga maritima.
  Proteins, 60, 552-557.
PDB code: 1t3v
15980471 L.Jaroszewski, L.Rychlewski, Z.Li, W.Li, and A.Godzik (2005).
FFAS03: a server for profile--profile sequence alignments.
  Nucleic Acids Res, 33, W284-W288.  
16167343 L.Jaroszewski, R.Schwarzenbacher, D.McMullan, P.Abdubek, S.Agarwalla, E.Ambing, H.Axelrod, T.Biorac, J.M.Canaves, H.J.Chiu, A.M.Deacon, M.DiDonato, M.A.Elsliger, A.Godzik, C.Grittini, S.K.Grzechnik, J.Hale, E.Hampton, G.W.Han, J.Haugen, M.Hornsby, H.E.Klock, E.Koesema, A.Kreusch, P.Kuhn, S.A.Lesley, M.D.Miller, K.Moy, E.Nigoghossian, J.Paulsen, K.Quijano, R.Reyes, C.Rife, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, A.White, G.Wolf, Q.Xu, K.O.Hodgson, J.Wooley, and I.A.Wilson (2005).
Crystal structure of Hsp33 chaperone (TM1394) from Thermotoga maritima at 2.20 A resolution.
  Proteins, 61, 669-673.
PDB code: 1vq0
15993809 M.Congreve, C.W.Murray, and T.L.Blundell (2005).
Structural biology and drug discovery.
  Drug Discov Today, 10, 895-907.  
15939017 M.Robinson-Rechavi, and A.Godzik (2005).
Structural genomics of thermotoga maritima proteins shows that contact order is a major determinant of protein thermostability.
  Structure, 13, 857-860.  
16199668 M.S.Almeida, T.Herrmann, W.Peti, I.A.Wilson, and K.Wüthrich (2005).
NMR structure of the conserved hypothetical protein TM0487 from Thermotoga maritima: implications for 216 homologous DUF59 proteins.
  Protein Sci, 14, 2880-2886.
PDB codes: 1uwd 1wcj
15965734 N.P.Cowieson, P.Listwan, M.Kurz, A.Aagaard, T.Ravasi, C.Wells, T.Huber, D.A.Hume, B.Kobe, and J.L.Martin (2005).
Pilot studies on the parallel production of soluble mouse proteins in a bacterial expression system.
  J Struct Funct Genomics, 6, 13-20.  
15651027 Q.Xu, R.Schwarzenbacher, D.McMullan, P.Abdubek, E.Ambing, T.Biorac, J.M.Canaves, H.J.Chiu, X.Dai, A.M.Deacon, M.DiDonato, M.A.Elsliger, A.Godzik, C.Grittini, S.K.Grzechnik, E.Hampton, M.Hornsby, L.Jaroszewski, H.E.Klock, E.Koesema, A.Kreusch, P.Kuhn, S.A.Lesley, I.Levin, M.D.Miller, A.Morse, K.Moy, J.Ouyang, R.Page, K.Quijano, R.Reyes, A.Robb, E.Sims, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, F.von Delft, X.Wang, B.West, A.White, G.Wolf, O.Zagnitko, K.O.Hodgson, J.Wooley, and I.A.Wilson (2005).
Crystal structure of a formiminotetrahydrofolate cyclodeaminase (TM1560) from Thermotoga maritima at 2.80 A resolution reveals a new fold.
  Proteins, 58, 976-981.
PDB code: 1o5h
16211521 R.Page, A.M.Deacon, S.A.Lesley, and R.C.Stevens (2005).
Shotgun crystallization strategy for structural genomics II: crystallization conditions that produce high resolution structures for T. maritima proteins.
  J Struct Funct Genomics, 6, 209-217.  
15677718 R.Page, W.Peti, I.A.Wilson, R.C.Stevens, and K.Wüthrich (2005).
NMR screening and crystal quality of bacterially expressed prokaryotic and eukaryotic proteins in a structural genomics pipeline.
  Proc Natl Acad Sci U S A, 102, 1901-1905.  
16211502 S.A.Lesley, and I.A.Wilson (2005).
Protein production and crystallization at the joint center for structural genomics.
  J Struct Funct Genomics, 6, 71-79.  
15689514 S.Eshaghi, M.Hedrén, M.I.Nasser, T.Hammarberg, A.Thornell, and P.Nordlund (2005).
An efficient strategy for high-throughput expression screening of recombinant integral membrane proteins.
  Protein Sci, 14, 676-683.  
16168087 S.M.Douglas, G.T.Montelione, and M.Gerstein (2005).
PubNet: a flexible system for visualizing literature derived networks.
  Genome Biol, 6, R80.  
15965733 W.B.Arendall, W.Tempel, J.S.Richardson, W.Zhou, S.Wang, I.W.Davis, Z.J.Liu, J.P.Rose, W.M.Carson, M.Luo, D.C.Richardson, and B.C.Wang (2005).
A test of enhancing model accuracy in high-throughput crystallography.
  J Struct Funct Genomics, 6, 1.  
16188992 W.Peti, M.A.Johnson, T.Herrmann, B.W.Neuman, M.J.Buchmeier, M.Nelson, J.Joseph, R.Page, R.C.Stevens, P.Kuhn, and K.Wüthrich (2005).
Structural genomics of the severe acute respiratory syndrome coronavirus: nuclear magnetic resonance structure of the protein nsP7.
  J Virol, 79, 12905-12913.
PDB code: 1ysy
16283429 W.Peti, R.Page, K.Moy, M.O'Neil-Johnson, I.A.Wilson, R.C.Stevens, and K.Wüthrich (2005).
Towards miniaturization of a structural genomics pipeline using micro-expression and microcoil NMR.
  J Struct Funct Genomics, 6, 259-267.  
15723348 W.Peti, T.Herrmann, O.Zagnitko, S.K.Grzechnik, and K.Wüthrich (2005).
NMR structure of the conserved hypothetical protein TM0979 from Thermotoga maritima.
  Proteins, 59, 387-390.
PDB code: 1rhx
15211522 A.Heine, J.M.Canaves, F.von Delft, L.S.Brinen, X.Dai, A.M.Deacon, M.A.Elsliger, S.Eshaghi, R.Floyd, A.Godzik, C.Grittini, S.K.Grzechnik, C.Guda, L.Jaroszewski, C.Karlak, H.E.Klock, E.Koesema, J.S.Kovarik, A.Kreusch, P.Kuhn, S.A.Lesley, D.McMullan, T.M.McPhillips, M.A.Miller, M.D.Miller, A.Morse, K.Moy, J.Ouyang, R.Page, A.Robb, K.Rodrigues, R.Schwarzenbacher, T.L.Selby, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, X.Wang, B.West, G.Wolf, K.O.Hodgson, J.Wooley, and I.A.Wilson (2004).
Crystal structure of O-acetylserine sulfhydrylase (TM0665) from Thermotoga maritima at 1.8 A resolution.
  Proteins, 56, 387-391.
PDB code: 1o58
15229892 C.Bakolitsa, R.Schwarzenbacher, D.McMullan, L.S.Brinen, J.M.Canaves, X.Dai, A.M.Deacon, M.A.Elsliger, S.Eshagi, R.Floyd, A.Godzik, C.Grittini, S.K.Grzechnik, L.Jaroszewski, C.Karlak, H.E.Klock, E.Koesema, J.S.Kovarik, A.Kreusch, P.Kuhn, S.A.Lesley, T.M.McPhillips, M.D.Miller, A.Morse, K.Moy, J.Ouyang, R.Page, K.Quijano, A.Robb, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, F.von Delft, X.Wang, B.West, G.Wolf, K.O.Hodgson, J.Wooley, and I.A.Wilson (2004).
Crystal structure of an orphan protein (TM0875) from Thermotoga maritima at 2.00-A resolution reveals a new fold.
  Proteins, 56, 607-610.
PDB code: 1o22
15489332 C.H.Luan, S.Qiu, J.B.Finley, M.Carson, R.J.Gray, W.Huang, D.Johnson, J.Tsao, J.Reboul, P.Vaglio, D.E.Hill, M.Vidal, L.J.Delucas, and M.Luo (2004).
High-throughput expression of C. elegans proteins.
  Genome Res, 14, 2102-2110.  
15229894 D.McMullan, R.Schwarzenbacher, L.Jaroszewski, F.von Delft, H.E.Klock, J.Vincent, K.Quijano, P.Abdubek, E.Ambing, T.Biorac, L.S.Brinen, J.M.Canaves, X.Dai, A.M.Deacon, M.DiDonato, M.A.Elsliger, S.Eshaghi, R.Floyd, A.Godzik, C.Grittini, S.K.Grzechnik, E.Hampton, C.Karlak, E.Koesema, A.Kreusch, P.Kuhn, I.Levin, T.M.McPhillips, M.D.Miller, A.Morse, K.Moy, J.Ouyang, R.Page, R.Reyes, F.Rezezadeh, A.Robb, E.Sims, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, X.Wang, B.West, G.Wolf, Q.Xu, K.O.Hodgson, J.Wooley, S.A.Lesley, and I.A.Wilson (2004).
Crystal structure of a novel Thermotoga maritima enzyme (TM1112) from the cupin family at 1.83 A resolution.
  Proteins, 56, 615-618.
PDB code: 1o5u
14715906 D.Pantazatos, J.S.Kim, H.E.Klock, R.C.Stevens, I.A.Wilson, S.A.Lesley, and V.L.Woods (2004).
Rapid refinement of crystallographic protein construct definition employing enhanced hydrogen/deuterium exchange MS.
  Proc Natl Acad Sci U S A, 101, 751-756.  
15162496 E.Santelli, R.Schwarzenbacher, D.McMullan, T.Biorac, L.S.Brinen, J.M.Canaves, J.Cambell, X.Dai, A.M.Deacon, M.A.Elsliger, S.Eshagi, R.Floyd, A.Godzik, C.Grittini, S.K.Grzechnik, L.Jaroszewski, C.Karlak, H.E.Klock, E.Koesema, J.S.Kovarik, A.Kreusch, P.Kuhn, S.A.Lesley, T.M.McPhillips, M.D.Miller, A.Morse, K.Moy, J.Ouyang, R.Page, K.Quijano, F.Rezezadeh, A.Robb, E.Sims, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, F.von Delft, X.Wang, B.West, G.Wolf, Q.Xu, K.O.Hodgson, J.Wooley, and I.A.Wilson (2004).
Crystal structure of a glycerophosphodiester phosphodiesterase (GDPD) from Thermotoga maritima (TM1621) at 1.60 A resolution.
  Proteins, 56, 167-170.
PDB code: 1o1z
15557262 G.Spraggon, D.Pantazatos, H.E.Klock, I.A.Wilson, V.L.Woods, and S.A.Lesley (2004).
On the use of DXMS to produce more crystallizable proteins: structures of the T. maritima proteins TM0160 and TM1171.
  Protein Sci, 13, 3187-3199.
PDB codes: 1o5l 1sj5 1vjl
15146505 G.Spraggon, R.Schwarzenbacher, A.Kreusch, C.C.Lee, P.Abdubek, E.Ambing, T.Biorac, L.S.Brinen, J.M.Canaves, J.Cambell, H.J.Chiu, X.Dai, A.M.Deacon, M.DiDonato, M.A.Elsliger, S.Eshagi, R.Floyd, A.Godzik, C.Grittini, S.K.Grzechnik, E.Hampton, L.Jaroszewski, C.Karlak, H.E.Klock, E.Koesema, J.S.Kovarik, P.Kuhn, I.Levin, D.McMullan, T.M.McPhillips, M.D.Miller, A.Morse, K.Moy, J.Ouyang, R.Page, K.Quijano, A.Robb, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, F.von Delft, X.Wang, B.West, G.Wolf, Q.Xu, K.O.Hodgson, J.Wooley, S.A.Lesley, and I.A.Wilson (2004).
Crystal structure of an Udp-n-acetylmuramate-alanine ligase MurC (TM0231) from Thermotoga maritima at 2.3 A resolution.
  Proteins, 55, 1078-1081.
PDB code: 1j6u
15211524 G.Spraggon, R.Schwarzenbacher, A.Kreusch, D.McMullan, L.S.Brinen, J.M.Canaves, X.Dai, A.M.Deacon, M.A.Elsliger, S.Eshagi, R.Floyd, A.Godzik, C.Grittini, S.K.Grzechnik, L.Jaroszewski, C.Karlak, H.E.Klock, E.Koesema, J.S.Kovarik, P.Kuhn, T.M.McPhillips, M.D.Miller, A.Morse, K.Moy, J.Ouyang, R.Page, K.Quijano, F.Rezezadeh, A.Robb, E.Sims, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, F.von Delft, X.Wang, B.West, G.Wolf, Q.Xu, K.O.Hodgson, J.Wooley, S.A.Lesley, and I.A.Wilson (2004).
Crystal structure of a methionine aminopeptidase (TM1478) from Thermotoga maritima at 1.9 A resolution.
  Proteins, 56, 396-400.
PDB code: 1o0x
14997578 H.Erlandsen, J.M.Canaves, M.A.Elsliger, F.von Delft, L.S.Brinen, X.Dai, A.M.Deacon, R.Floyd, A.Godzik, C.Grittini, S.K.Grzechnik, L.Jaroszewski, H.E.Klock, E.Koesema, J.S.Kovarik, A.Kreusch, P.Kuhn, S.A.Lesley, D.McMullan, T.M.McPhillips, M.D.Miller, A.Morse, K.Moy, J.Ouyang, R.Page, A.Robb, K.Quijano, R.Schwarzenbacher, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, X.Wang, B.West, G.Wolf, K.O.Hodgson, J.Wooley, and I.A.Wilson (2004).
Crystal structure of an HEPN domain protein (TM0613) from Thermotoga maritima at 1.75 A resolution.
  Proteins, 54, 806-809.
PDB code: 1o3u
15229897 I.Levin, R.Schwarzenbacher, D.McMullan, P.Abdubek, E.Ambing, T.Biorac, J.Cambell, J.M.Canaves, H.J.Chiu, X.Dai, A.M.Deacon, M.DiDonato, M.A.Elsliger, A.Godzik, C.Grittini, S.K.Grzechnik, E.Hampton, L.Jaroszewski, C.Karlak, H.E.Klock, E.Koesema, A.Kreusch, P.Kuhn, S.A.Lesley, T.M.McPhillips, M.D.Miller, A.Morse, K.Moy, J.Ouyang, R.Page, K.Quijano, R.Reyes, A.Robb, E.Sims, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, F.von Delft, X.Wang, B.West, G.Wolf, Q.Xu, K.O.Hodgson, J.Wooley, and I.A.Wilson (2004).
Crystal structure of a putative NADPH-dependent oxidoreductase (GI: 18204011) from mouse at 2.10 A resolution.
  Proteins, 56, 629-633.
PDB code: 1vj1
15211526 I.Levin, R.Schwarzenbacher, R.Page, P.Abdubek, E.Ambing, T.Biorac, L.S.Brinen, J.Campbell, J.M.Canaves, H.J.Chiu, X.Dai, A.M.Deacon, M.DiDonato, M.A.Elsliger, R.Floyd, A.Godzik, C.Grittini, S.K.Grzechnik, E.Hampton, L.Jaroszewski, C.Karlak, H.E.Klock, E.Koesema, J.S.Kovarik, A.Kreusch, P.Kuhn, S.A.Lesley, D.McMullan, T.M.McPhillips, M.D.Miller, A.Morse, K.Moy, J.Ouyang, K.Quijano, R.Reyes, F.Rezezadeh, A.Robb, E.Sims, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, F.von Delft, X.Wang, B.West, G.Wolf, Q.Xu, K.O.Hodgson, J.Wooley, and I.A.Wilson (2004).
Crystal structure of a PIN (PilT N-terminus) domain (AF0591) from Archaeoglobus fulgidus at 1.90 A resolution.
  Proteins, 56, 404-408.
PDB code: 1o4w
15162483 J.M.Canaves (2004).
Predicted role for the archease protein family based on structural and sequence analysis of TM1083 and MTH1598, two proteins structurally characterized through structural genomics efforts.
  Proteins, 56, 19-27.  
15229893 L.Jaroszewski, R.Schwarzenbacher, F.von Delft, D.McMullan, L.S.Brinen, J.M.Canaves, X.Dai, A.M.Deacon, M.DiDonato, M.A.Elsliger, S.Eshagi, R.Floyd, A.Godzik, C.Grittini, S.K.Grzechnik, E.Hampton, I.Levin, C.Karlak, H.E.Klock, E.Koesema, J.S.Kovarik, A.Kreusch, P.Kuhn, S.A.Lesley, T.M.McPhillips, M.D.Miller, A.Morse, K.Moy, J.Ouyang, R.Page, K.Quijano, R.Reyes, F.Rezezadeh, A.Robb, E.Sims, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, X.Wang, B.West, G.Wolf, Q.Xu, K.O.Hodgson, J.Wooley, and I.A.Wilson (2004).
Crystal structure of a novel manganese-containing cupin (TM1459) from Thermotoga maritima at 1.65 A resolution.
  Proteins, 56, 611-614.
PDB code: 1vj2
15372084 M.B.Schmid (2004).
Seeing is believing: the impact of structural genomics on antimicrobial drug discovery.
  Nat Rev Microbiol, 2, 739-746.  
15333954 M.C.Burla, B.Carrozzini, G.L.Cascarano, C.Giacovazzo, M.Moustiakimov, G.Polidori, and D.Siliqi (2004).
MAD phasing: choosing the most informative wavelength combination.
  Acta Crystallogr D Biol Crystallogr, 60, 1683-1686.  
15326606 M.D.Miller, R.Schwarzenbacher, F.von Delft, P.Abdubek, E.Ambing, T.Biorac, L.S.Brinen, J.M.Canaves, J.Cambell, H.J.Chiu, X.Dai, A.M.Deacon, M.DiDonato, M.A.Elsliger, S.Eshagi, R.Floyd, A.Godzik, C.Grittini, S.K.Grzechnik, E.Hampton, L.Jaroszewski, C.Karlak, H.E.Klock, E.Koesema, J.S.Kovarik, A.Kreusch, P.Kuhn, S.A.Lesley, I.Levin, D.McMullan, T.M.McPhillips, A.Morse, K.Moy, J.Ouyang, R.Page, K.Quijano, A.Robb, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, X.Wang, B.West, G.Wolf, Q.Xu, K.O.Hodgson, J.Wooley, and I.A.Wilson (2004).
Crystal structure of a tandem cystathionine-beta-synthase (CBS) domain protein (TM0935) from Thermotoga maritima at 1.87 A resolution.
  Proteins, 57, 213-217.
PDB code: 1o50
15342584 M.L.Fernández-Murga, F.Gil-Ortiz, J.L.Llácer, and V.Rubio (2004).
Arginine biosynthesis in Thermotoga maritima: characterization of the arginine-sensitive N-acetyl-L-glutamate kinase.
  J Bacteriol, 186, 6142-6149.  
15489337 M.R.Chance, A.Fiser, A.Sali, U.Pieper, N.Eswar, G.Xu, J.E.Fajardo, T.Radhakannan, and N.Marinkovic (2004).
High-throughput computational and experimental techniques in structural genomics.
  Genome Res, 14, 2145-2154.  
15211505 N.O'Toole, M.Grabowski, Z.Otwinowski, W.Minor, and M.Cygler (2004).
The structural genomics experimental pipeline: insights from global target lists.
  Proteins, 56, 201-210.  
15162497 Q.Xu, R.Schwarzenbacher, D.McMullan, F.von Delft, L.S.Brinen, J.M.Canaves, X.Dai, A.M.Deacon, M.A.Elsliger, S.Eshagi, R.Floyd, A.Godzik, C.Grittini, S.K.Grzechnik, L.Jaroszewski, C.Karlak, H.E.Klock, E.Koesema, J.S.Kovarik, A.Kreusch, P.Kuhn, S.A.Lesley, I.Levin, T.M.McPhillips, M.D.Miller, A.Morse, K.Moy, J.Ouyang, R.Page, K.Quijano, A.Robb, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, X.Wang, B.West, G.Wolf, K.O.Hodgson, J.Wooley, and I.A.Wilson (2004).
Crystal structure of a ribose-5-phosphate isomerase RpiB (TM1080) from Thermotoga maritima at 1.90 A resolution.
  Proteins, 56, 171-175.
PDB code: 1o1x
15229895 Q.Xu, R.Schwarzenbacher, R.Page, E.Sims, P.Abdubek, E.Ambing, T.Biorac, L.S.Brinen, J.Cambell, J.M.Canaves, H.J.Chiu, X.Dai, A.M.Deacon, M.DiDonato, M.A.Elsliger, R.Floyd, A.Godzik, C.Grittini, S.K.Grzechnik, E.Hampton, L.Jaroszewski, C.Karlak, H.E.Klock, E.Koesema, J.S.Kovarik, A.Kreusch, P.Kuhn, S.A.Lesley, I.Levin, D.McMullan, T.M.McPhillips, M.D.Miller, A.Morse, K.Moy, J.Ouyang, K.Quijano, R.Reyes, F.Rezezadeh, A.Robb, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, F.von Delft, X.Wang, B.West, G.Wolf, K.O.Hodgson, J.Wooley, and I.A.Wilson (2004).
Crystal structure of an allantoicase (YIR029W) from Saccharomyces cerevisiae at 2.4 A resolution.
  Proteins, 56, 619-624.
PDB code: 1o59
15048098 R.C.Stevens (2004).
Long live structural biology.
  Nat Struct Mol Biol, 11, 293-295.  
14705032 R.Page, M.S.Nelson, F.von Delft, M.A.Elsliger, J.M.Canaves, L.S.Brinen, X.Dai, A.M.Deacon, R.Floyd, A.Godzik, C.Grittini, S.K.Grzechnik, L.Jaroszewski, H.E.Klock, E.Koesema, J.S.Kovarik, A.Kreusch, P.Kuhn, S.A.Lesley, D.McMullan, T.M.McPhillips, M.D.Miller, A.Morse, K.Moy, J.Ouyang, A.Robb, K.Rodrigues, R.Schwarzenbacher, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, X.Wang, B.West, G.Wolf, K.O.Hodgson, J.Wooley, and I.A.Wilson (2004).
Crystal structure of gamma-glutamyl phosphate reductase (TM0293) from Thermotoga maritima at 2.0 A resolution.
  Proteins, 54, 157-161.
PDB code: 1o20
14997577 R.Schwarzenbacher, A.M.Deacon, L.Jaroszewski, L.S.Brinen, J.M.Canaves, X.Dai, M.A.Elsliger, R.Floyd, A.Godzik, C.Grittini, S.K.Grzechnik, H.E.Klock, E.Koesema, J.S.Kovarik, A.Kreusch, P.Kuhn, S.A.Lesley, D.McMullan, T.M.McPhillips, M.D.Miller, A.Morse, K.Moy, M.S.Nelson, J.Ouyang, R.Page, A.Robb, K.Quijano, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, F.von Delft, X.Wang, B.West, G.Wolf, K.O.Hodgson, J.Wooley, and I.A.Wilson (2004).
Crystal structure of a putative glutamine amido transferase (TM1158) from Thermotoga maritima at 1.7 A resolution.
  Proteins, 54, 801-805.
PDB code: 1o1y
14705036 R.Schwarzenbacher, F.von Delft, J.M.Canaves, L.S.Brinen, X.Dai, A.M.Deacon, M.A.Elsliger, S.Eshaghi, R.Floyd, A.Godzik, C.Grittini, S.K.Grzechnik, C.Guda, L.Jaroszewski, C.Karlak, H.E.Klock, E.Koesema, J.S.Kovarik, A.Kreusch, P.Kuhn, S.A.Lesley, D.McMullan, T.M.McPhillips, M.A.Miller, M.D.Miller, A.Morse, K.Moy, J.Ouyang, R.Page, A.Robb, K.Rodrigues, T.L.Selby, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, X.Wang, B.West, G.Wolf, K.O.Hodgson, J.Wooley, and I.A.Wilson (2004).
Crystal structure of an iron-containing 1,3-propanediol dehydrogenase (TM0920) from Thermotoga maritima at 1.3 A resolution.
  Proteins, 54, 174-177.
PDB code: 1o2d
15211523 R.Schwarzenbacher, F.von Delft, L.Jaroszewski, P.Abdubek, E.Ambing, T.Biorac, L.S.Brinen, J.M.Canaves, J.Cambell, H.J.Chiu, X.Dai, A.M.Deacon, M.DiDonato, M.A.Elsliger, S.Eshagi, R.Floyd, A.Godzik, C.Grittini, S.K.Grzechnik, E.Hampton, C.Karlak, H.E.Klock, E.Koesema, J.S.Kovarik, A.Kreusch, P.Kuhn, S.A.Lesley, I.Levin, D.McMullan, T.M.McPhillips, M.D.Miller, A.Morse, K.Moy, J.Ouyang, R.Page, K.Quijano, A.Robb, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, X.Wang, B.West, G.Wolf, Q.Xu, K.O.Hodgson, J.Wooley, and I.A.Wilson (2004).
Crystal structure of a putative oxalate decarboxylase (TM1287) from Thermotoga maritima at 1.95 A resolution.
  Proteins, 56, 392-395.
PDB code: 1o4t
14997579 R.Schwarzenbacher, F.von Delft, P.Abdubek, E.Ambing, T.Biorac, L.S.Brinen, J.M.Canaves, J.Cambell, H.J.Chiu, X.Dai, A.M.Deacon, M.DiDonato, M.A.Elsliger, S.Eshagi, R.Floyd, A.Godzik, C.Grittini, S.K.Grzechnik, E.Hampton, L.Jaroszewski, C.Karlak, H.E.Klock, E.Koesema, J.S.Kovarik, A.Kreusch, P.Kuhn, S.A.Lesley, I.Levin, D.McMullan, T.M.McPhillips, M.D.Miller, A.Morse, K.Moy, J.Ouyang, R.Page, K.Quijano, A.Robb, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, X.Wang, B.West, G.Wolf, Q.Xu, K.O.Hodgson, J.Wooley, and I.A.Wilson (2004).
Crystal structure of a putative PII-like signaling protein (TM0021) from Thermotoga maritima at 2.5 A resolution.
  Proteins, 54, 810-813.
PDB code: 1o51
15048837 R.Schwarzenbacher, L.Jaroszewski, F.von Delft, P.Abdubek, E.Ambing, T.Biorac, L.S.Brinen, J.M.Canaves, J.Cambell, H.J.Chiu, X.Dai, A.M.Deacon, M.DiDonato, M.A.Elsliger, S.Eshagi, R.Floyd, A.Godzik, C.Grittini, S.K.Grzechnik, E.Hampton, C.Karlak, H.E.Klock, E.Koesema, J.S.Kovarik, A.Kreusch, P.Kuhn, S.A.Lesley, I.Levin, D.McMullan, T.M.McPhillips, M.D.Miller, A.Morse, K.Moy, J.Ouyang, R.Page, K.Quijano, A.Robb, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, X.Wang, B.West, G.Wolf, Q.Xu, K.O.Hodgson, J.Wooley, and I.A.Wilson (2004).
Crystal structure of a phosphoribosylaminoimidazole mutase PurE (TM0446) from Thermotoga maritima at 1.77-A resolution.
  Proteins, 55, 474-478.
PDB code: 1o4v
15103638 R.Schwarzenbacher, L.Jaroszewski, F.von Delft, P.Abdubek, E.Ambing, T.Biorac, L.S.Brinen, J.M.Canaves, J.Cambell, H.J.Chiu, X.Dai, A.M.Deacon, M.DiDonato, M.A.Elsliger, S.Eshagi, R.Floyd, A.Godzik, C.Grittini, S.K.Grzechnik, E.Hampton, C.Karlak, H.E.Klock, E.Koesema, J.S.Kovarik, A.Kreusch, P.Kuhn, S.A.Lesley, I.Levin, D.McMullan, T.M.McPhillips, M.D.Miller, A.Morse, K.Moy, J.Ouyang, R.Page, K.Quijano, A.Robb, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, X.Wang, B.West, G.Wolf, Q.Xu, K.O.Hodgson, J.Wooley, and I.A.Wilson (2004).
Crystal structure of an aspartate aminotransferase (TM1255) from Thermotoga maritima at 1.90 A resolution.
  Proteins, 55, 759-763.
PDB code: 1o4s
15103640 R.Schwarzenbacher, L.Jaroszewski, F.von Delft, P.Abdubek, E.Ambing, T.Biorac, L.S.Brinen, J.M.Canaves, J.Cambell, H.J.Chiu, X.Dai, A.M.Deacon, M.DiDonato, M.A.Elsliger, S.Eshagi, R.Floyd, A.Godzik, C.Grittini, S.K.Grzechnik, E.Hampton, C.Karlak, H.E.Klock, E.Koesema, J.S.Kovarik, A.Kreusch, P.Kuhn, S.A.Lesley, I.Levin, D.McMullan, T.M.McPhillips, M.D.Miller, A.Morse, K.Moy, J.Ouyang, R.Page, K.Quijano, A.Robb, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, X.Wang, B.West, G.Wolf, Q.Xu, K.O.Hodgson, J.Wooley, and I.A.Wilson (2004).
Crystal structure of a type II quinolic acid phosphoribosyltransferase (TM1645) from Thermotoga maritima at 2.50 A resolution.
  Proteins, 55, 768-771.
PDB code: 1o4u
15342603 X.Q.Liu, and J.Yang (2004).
Bacterial thymidylate synthase with intein, group II Intron, and distinctive ThyX motifs.
  J Bacteriol, 186, 6316-6319.  
15263850 Y.Kim, I.Dementieva, M.Zhou, R.Wu, L.Lezondra, P.Quartey, G.Joachimiak, O.Korolev, H.Li, and A.Joachimiak (2004).
Automation of protein purification for structural genomics.
  J Struct Funct Genomics, 5, 111-118.  
  15215455 Y.Ye, and A.Godzik (2004).
FATCAT: a web server for flexible structure comparison and structure similarity searching.
  Nucleic Acids Res, 32, W582-W585.  
15215527 Y.Ye, and A.Godzik (2004).
Database searching by flexible protein structure alignment.
  Protein Sci, 13, 1841-1850.  
12554942 A.González (2003).
Faster data-collection strategies for structure determination using anomalous dispersion.
  Acta Crystallogr D Biol Crystallogr, 59, 315-322.  
12837772 A.Matte, J.Sivaraman, I.Ekiel, K.Gehring, Z.Jia, and M.Cygler (2003).
Contribution of structural genomics to understanding the biology of Escherichia coli.
  J Bacteriol, 185, 3994-4002.  
14506850 D.Frishman (2003).
What we have learned about prokaryotes from structural genomics.
  OMICS, 7, 211-224.  
12486729 L.S.Brinen, J.M.Canaves, X.Dai, A.M.Deacon, M.A.Elsliger, S.Eshaghi, R.Floyd, A.Godzik, C.Grittini, S.K.Grzechnik, C.Guda, L.Jaroszewski, C.Karlak, H.E.Klock, E.Koesema, J.S.Kovarik, A.Kreusch, P.Kuhn, S.A.Lesley, D.McMullan, T.M.McPhillips, M.A.Miller, M.D.Miller, A.Morse, K.Moy, J.Ouyang, A.Robb, K.Rodrigues, T.L.Selby, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, X.Wang, B.West, G.Wolf, S.S.Taylor, K.O.Hodgson, J.Wooley, and I.A.Wilson (2003).
Crystal structure of a zinc-containing glycerol dehydrogenase (TM0423) from Thermotoga maritima at 1.5 A resolution.
  Proteins, 50, 371-374.  
12657785 M.C.Burla, B.Carrozzini, G.L.Cascarano, C.Giacovazzo, and G.Polidori (2003).
SAD or MAD phasing: location of the anomalous scatterers.
  Acta Crystallogr D Biol Crystallogr, 59, 662-669.  
12777766 R.Page, S.K.Grzechnik, J.M.Canaves, G.Spraggon, A.Kreusch, P.Kuhn, R.C.Stevens, and S.A.Lesley (2003).
Shotgun crystallization strategy for structural genomics: an optimized two-tiered crystallization screen against the Thermotoga maritima proteome.
  Acta Crystallogr D Biol Crystallogr, 59, 1028-1037.  
12945057 R.Schwarzenbacher, J.M.Canaves, L.S.Brinen, X.Dai, A.M.Deacon, M.A.Elsliger, S.Eshaghi, R.Floyd, A.Godzik, C.Grittini, S.K.Grzechnik, C.Guda, L.Jaroszewski, C.Karlak, H.E.Klock, E.Koesema, J.S.Kovarik, A.Kreusch, P.Kuhn, S.A.Lesley, D.McMullan, T.M.McPhillips, M.A.Miller, M.D.Miller, A.Morse, K.Moy, J.Ouyang, A.Robb, K.Rodrigues, T.L.Selby, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, X.Wang, B.West, G.Wolf, K.O.Hodgson, J.Wooley, and I.A.Wilson (2003).
Crystal structure of uronate isomerase (TM0064) from Thermotoga maritima at 2.85 A resolution.
  Proteins, 53, 142-145.
PDB code: 1j5s
  18629095 , (2003).
Current awareness on comparative and functional genomics.
  Comp Funct Genomics, 4, 161-168.  
12788548 A.Bradbury, N.Velappan, V.Verzillo, M.Ovecka, L.Chasteen, D.Sblattero, R.Marzari, J.Lou, R.Siegel, and P.Pavlik (2003).
Antibodies in proteomics I: generating antibodies.
  Trends Biotechnol, 21, 275-281.  
12826121 A.Sharff, and H.Jhoti (2003).
High-throughput crystallography to enhance drug discovery.
  Curr Opin Chem Biol, 7, 340-345.  
12547423 C.Zhang, and S.H.Kim (2003).
Overview of structural genomics: from structure to function.
  Curr Opin Chem Biol, 7, 28-32.  
12765831 M.Grynberg, H.Erlandsen, and A.Godzik (2003).
HEPN: a common domain in bacterial drug resistance and human neurodegenerative proteins.
  Trends Biochem Sci, 28, 224-226.  
12948670 P.Braun, and J.LaBaer (2003).
High throughput protein production for functional proteomics.
  Trends Biotechnol, 21, 383-388.  
12547425 S.Yokoyama (2003).
Protein expression systems for structural genomics and proteomics.
  Curr Opin Chem Biol, 7, 39-43.  
12393922 G.Spraggon, S.A.Lesley, A.Kreusch, and J.P.Priestle (2002).
Computational analysis of crystallization trials.
  Acta Crystallogr D Biol Crystallogr, 58, 1915-1923.  
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time. Where a reference describes a PDB structure, the PDB code is shown on the right.

 

spacer
spacer