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PDBsum entry 1f9r
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Contents |
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* Residue conservation analysis
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PDB id:
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Cytokine
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Title:
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Crystal structure of platelet factor 4 mutant 1
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Structure:
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Platelet factor 4. Chain: a, b, c, d. Synonym: pf-4, oncostatin, iroplact. Engineered: yes. Mutation: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Biol. unit:
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Tetramer (from
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Resolution:
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2.00Å
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R-factor:
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0.224
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R-free:
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0.273
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Authors:
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J.Yang,M.Doyle,T.Faulk,G.Visentin,R.Aster,B.Edwards
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Key ref:
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J.Yang
et al.
Structure comparison of two platelet factor 4 mutants with the wild-Type reveals the epitopes for the heparin-Induced thrombocytopenia antibodies.
To be published,
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Date:
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11-Jul-00
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Release date:
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26-Aug-03
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PROCHECK
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Headers
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References
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P02776
(PLF4_HUMAN) -
Platelet factor 4 from Homo sapiens
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Seq:
Struc:
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101 a.a.
65 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 3 residue positions (black
crosses)
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Links
