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PDBsum entry 1f1f
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Electron transport
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PDB id
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1f1f
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Contents |
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* Residue conservation analysis
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DOI no:
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Biochemistry
40:9215-9225
(2001)
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PubMed id:
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Structures of cytochrome c-549 and cytochrome c6 from the cyanobacterium Arthrospira maxima.
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M.R.Sawaya,
D.W.Krogmann,
A.Serag,
K.K.Ho,
T.O.Yeates,
C.A.Kerfeld.
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ABSTRACT
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Cytochrome c(6) and cytochrome c-549 are small (89 and 130 amino acids,
respectively) monoheme cytochromes that function in photosynthesis. They appear
to have descended relatively recently from the same ancestral gene but have
diverged to carry out very different functional roles, underscored by the large
difference between their midpoint potentials of nearly 600 mV. We have
determined the X-ray crystal structures of both proteins isolated from the
cyanobacterium Arthrospira maxima. The two structures are remarkably similar,
superimposing on backbone atoms with an rmsd of 0.7 A. Comparison of the two
structures suggests that differences in solvent exposure of the heme and the
electrostatic environment of the heme propionates, as well as in heme iron
ligation, are the main determinants of midpoint potential in the two proteins.
In addition, the crystal packing of both A. maxima cytochrome c-549 and
cytochrome c(6) suggests that the proteins oligomerize. Finally, the cytochrome
c-549 dimer we observe can be readily fit into the recently described model of
cyanobacterial photosystem II.
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Literature references that cite this PDB file's key reference
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PubMed id
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Reference
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B.S.Rajagopal,
M.T.Wilson,
D.S.Bendall,
C.J.Howe,
and
J.A.Worrall
(2011).
Structural and kinetic studies of imidazole binding to two members of the cytochrome c (6) family reveal an important role for a conserved heme pocket residue.
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J Biol Inorg Chem,
16,
577-588.
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PDB code:
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H.Akazaki,
F.Kawai,
M.Hosokawa,
T.Hama,
H.Chida,
T.Hirano,
B.K.Lim,
N.Sakurai,
W.Hakamata,
S.Y.Park,
T.Nishio,
and
T.Oku
(2009).
Crystallization and structural analysis of cytochrome c(6) from the diatom Phaeodactylum tricornutum at 1.5 A resolution.
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Biosci Biotechnol Biochem,
73,
189-191.
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PDB code:
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W.Bialek,
S.Krzywda,
M.Jaskolski,
and
A.Szczepaniak
(2009).
Atomic-resolution structure of reduced cyanobacterial cytochrome c6 with an unusual sequence insertion.
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FEBS J,
276,
4426-4436.
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PDB code:
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H.Akazaki,
F.Kawai,
H.Chida,
Y.Matsumoto,
M.Hirayama,
K.Hoshikawa,
S.Unzai,
W.Hakamata,
T.Nishio,
S.Y.Park,
and
T.Oku
(2008).
Cloning, expression and purification of cytochrome c(6) from the brown alga Hizikia fusiformis and complete X-ray diffraction analysis of the structure.
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Acta Crystallogr Sect F Struct Biol Cryst Commun,
64,
674-680.
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PDB code:
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I.Enami,
A.Okumura,
R.Nagao,
T.Suzuki,
M.Iwai,
and
J.R.Shen
(2008).
Structures and functions of the extrinsic proteins of photosystem II from different species.
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Photosynth Res,
98,
349-363.
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P.Lukat,
M.Hoffmann,
and
O.Einsle
(2008).
Crystal packing of the c(6)-type cytochrome OmcF from Geobacter sulfurreducens is mediated by an N-terminal Strep-tag II.
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Acta Crystallogr D Biol Crystallogr,
64,
919-926.
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PDB code:
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C.Lange,
I.Luque,
M.Hervás,
J.Ruiz-Sanz,
P.L.Mateo,
and
M.A.De la Rosa
(2005).
Role of the surface charges D72 and K8 in the function and structural stability of the cytochrome c from Nostoc sp. PCC 7119.
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FEBS J,
272,
3317-3327.
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J.De Las Rivas,
M.Balsera,
and
J.Barber
(2004).
Evolution of oxygenic photosynthesis: genome-wide analysis of the OEC extrinsic proteins.
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Trends Plant Sci,
9,
18-25.
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K.Ifuku,
T.Nakatsu,
H.Kato,
and
F.Sato
(2004).
Crystal structure of the PsbP protein of photosystem II from Nicotiana tabacum.
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EMBO Rep,
5,
362-367.
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PDB code:
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M.Balsera,
J.B.Arellano,
F.Pazos,
D.Devos,
A.Valencia,
and
J.De Las Rivas
(2003).
The single tryptophan of the PsbQ protein of photosystem II is at the end of a 4-alpha-helical bundle domain.
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Eur J Biochem,
270,
3916-3927.
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N.Kamiya,
and
J.R.Shen
(2003).
Crystal structure of oxygen-evolving photosystem II from Thermosynechococcus vulcanus at 3.7-A resolution.
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Proc Natl Acad Sci U S A,
100,
98.
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PDB code:
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C.A.Kerfeld,
M.R.Sawaya,
D.W.Krogmann,
and
T.O.Yeates
(2002).
Structure of cytochrome c6 from Arthrospira maxima: an assembly of 24 subunits in a nearly symmetric shell.
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Acta Crystallogr D Biol Crystallogr,
58,
1104-1110.
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PDB code:
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P.B.Crowley,
A.Díaz-Quintana,
F.P.Molina-Heredia,
P.Nieto,
M.Sutter,
W.Haehnel,
M.A.De La Rosa,
and
M.Ubbink
(2002).
The interactions of cyanobacterial cytochrome c6 and cytochrome f, characterized by NMR.
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J Biol Chem,
277,
48685-48689.
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The most recent references are shown first.
Citation data come partly from CiteXplore and partly
from an automated harvesting procedure. Note that this is likely to be
only a partial list as not all journals are covered by
either method. However, we are continually building up the citation data
so more and more references will be included with time.
Where a reference describes a PDB structure, the PDB
code is
shown on the right.
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