PDBsum entry 1v5e

Oxidoreductase

PDB id: 1v5e

Contents

Protein chain

590 a.a. *

Ligands

SO4 ×4

FAD

Waters ×719

* Residue conservation analysis

PDB id:

1v5e

Name:

Oxidoreductase

Title:

Crystal structure of pyruvate oxidase containing fad, from aerococcus viridans

Structure:

Pyruvate oxidase. Chain: a. Ec: 1.2.3.3

Source:

Aerococcus viridans. Organism_taxid: 1377

Biol. unit:

Tetramer (from PDB file)

Resolution:

1.60Å R-factor: 0.231 R-free: 0.250

Authors:

M.T.Hossain,K.Suzuki,T.Yamamoto,S.Imamura,T.Sekiguchi,A.Takenaka

Key ref:

M.T.Hossain et al. Crystal structure of pyruvate oxidase containing FAD, From aerococcus viridans. To be published, .

Date:

22-Nov-03 Release date: 28-Jun-05

Protein chain

A9X9K8  (A9X9K8_9LACT) -  Pyruvate oxidase (Fragment) from Aerococcus viridans

Seq: 592 a.a.

Struc: 590 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.1.2.3.3 - pyruvate oxidase.
• Reaction: pyruvate + phosphate + O2 + H⁺ = acetyl phosphate + H2O2 + CO2
• Cofactor: FAD; Thiamine diphosphate

FAD (Bound ligand (Het Group name = FAD) corresponds exactly) Thiamine diphosphate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site