OLDERADO

OLDERADO cluster and domain composition for PDB entry 2H35

Solution structure of Human normal adult hemoglobin
Summary of Olderado results
Most representative model 5
Largest domain comprises residues A.7-A.17, A.19-A.30, A.56-A.78, A.118-A.137
RMSD of all models in ensemble (Cα atoms) 1.6 Å

Protein domains shown as surfaces Representative models from each cluster
View in 3D View in 3D

Domain composition (NMRCore)
Domain number and colour code Residues Core Cumulative core
1 A.7-A.17, A.19-A.30, A.56-A.78, A.118-A.137 12.6 % 12.6 %
2 C.6-C.17, C.19-C.30, C.57-C.78, C.118-C.137 12.6 % 25.1 %
3 D.25-D.35, D.63-D.71 3.8 % 28.9 %
4 D.126-D.144 3.6 % 32.6 %
5 B.126-B.141 3.0 % 35.6 %
6 B.7-B.13, B.67-B.74 2.9 % 38.5 %
7 B.85-B.99 2.9 % 41.3 %
8 D.85-D.99 2.9 % 44.2 %
9 A.94-A.106 2.5 % 46.7 %
10 B.25-B.37 2.5 % 49.2 %
11 B.113-B.125 2.5 % 51.6 %
12 C.94-C.106 2.5 % 54.1 %
13 D.7-D.15, D.72-D.75 2.5 % 56.6 %
14 D.113-D.125 2.5 % 59.1 %
15 B.14-B.24 2.1 % 61.2 %
16 B.102-B.112 2.1 % 63.3 %
17 D.102-D.112 2.1 % 65.4 %
18 A.79-A.88 1.9 % 67.3 %
19 B.57-B.66 1.9 % 69.2 %
20 C.79-C.88 1.9 % 71.1 %
21 B.48-B.56 1.7 % 72.8 %
22 D.16-D.24 1.7 % 74.5 %
23 D.48-D.55 1.5 % 76.0 %
24 D.56-D.62 1.3 % 77.3 %
25 A.107-A.112 1.1 % 78.5 %
26 C.107-C.112 1.1 % 79.6 %
27 B.2-B.6 0.9 % 80.6 %
28 B.75-B.79 0.9 % 81.5 %
29 B.80-B.84 0.9 % 82.5 %
30 D.2-D.6 0.9 % 83.4 %
31 D.80-D.84 0.9 % 84.4 %
32 A.37-A.40 0.8 % 85.1 %
33 A.49-A.52 0.8 % 85.9 %
34 B.42-B.45 0.8 % 86.7 %
35 C.37-C.40 0.8 % 87.4 %
36 C.49-C.52 0.8 % 88.2 %
37 C.53-C.56 0.8 % 88.9 %
38 D.42-D.45 0.8 % 89.7 %
39 D.76-D.79 0.8 % 90.5 %
40 A.31-A.33 0.6 % 91.0 %
41 A.34-A.36 0.6 % 91.6 %
42 A.53-A.55 0.6 % 92.2 %
43 A.113-A.115 0.6 % 92.7 %
44 B.142-B.144 0.6 % 93.3 %
45 C.3-C.5 0.6 % 93.9 %
46 C.31-C.33 0.6 % 94.4 %
47 C.34-C.36 0.6 % 95.0 %
48 C.113-C.115 0.6 % 95.6 %
49 D.36-D.38 0.6 % 96.2 %
50 A.3-A.4 0.4 % 96.5 %
51 A.5-A.6 0.4 % 96.9 %
52 A.41-A.42 0.4 % 97.3 %
53 A.45-A.46 0.4 % 97.7 %
54 A.116-A.117 0.4 % 98.1 %
55 B.100-B.101 0.4 % 98.4 %
56 C.41-C.42 0.4 % 98.8 %
57 C.45-C.46 0.4 % 99.2 %
58 C.116-C.117 0.4 % 99.6 %
59 D.100-D.101 0.4 % 100.0 %

Cluster identification (NMRClust)
Cluster number and colour code Representative Members
1 5 5, 8, 9, 12, 15, 18
2 7 1, 6, 7, 11, 16
3 14 3, 13, 14, 19, 20
4 10 4, 10
 
List of outliers (subfamily with one member): 2, 17