Bringing Structure to Biology
|01 Jan 2019||
The new PDBe calendar for 2019 starts with an image representing the connection and communication between nerve cells mediated by the AMPA-type glutamate receptor.
|01 Dec 2018||
Waves of Trouble
The image for December in our 2018 calendar depicts Hepatitis A virus and a common route of human infection with the virus, shellfish from polluted water.
Hepatitis A virus infects ∼1.4 million people annually (WHO, 2016) and, although there is a vaccine, there are no licensed therapeutic drugs.
|01 Nov 2018||
Signalling in motion
The image in PDBe’s 2018 calendar for November shows nerves and muscle tissue, and the molecule which we use to send signals between them.
|01 Oct 2018||
The enemies of our enemies
The image in our calendar for October shows a virus which can kill a bacterium. A bacterium that is responsible a disease which affects over 15 million people each year. What can we learn from viruses that attack our own attackers?
|01 Sep 2018||
Opening up a Wormhole
The image for September in our 2018 calendar depicts Lysenin, a molecular hole punch produced by garden earthworms.
Revealing Beautiful Biology
Earthworms produce lysenin as an immune mechanism. It helps protect the worm from infection by boring holes in the cell membrane of organisms pathogenic to the worm, causing the cell contents to leak out.
|01 Aug 2018||
Our calendar image for August focuses not on a protein, but on one of the thousands of small molecules in the Protein Data Bank. This particular molecule is vital in our continuing fight against infection and has a long forgotten history.
|01 Jul 2018||
Typhoid Mary and the Indestructible Bacterium
|01 Jun 2018||
Dengue Virus: A Trojan Horse of the Molecular World
The image for June in our 2018 calendar depicts the Dengue Virus (DENV). This virus is responsible for dengue fever, a disease found in low-income populations within tropical areas within Africa, Asia, and the Americas.
|01 May 2018||
Stop motion: The muscular system
|01 Apr 2018||
Viruses: Engineering on the nanoscale
The image for April in our 2018 calendar depicts a single Zika virus protein in addition to the full Zika virus capsid. In this feature we discuss the transition between these two structures and demonstrate the beautiful simplicity of virus assembly.