Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Plasminogen activator inhibitor 1 (preferred)
PDBe Complex ID:
PDB-CPX-138524 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Plasminogen activator inhibitor 1
Molecule details ›
Chain: A
Length: 346 amino acids
Theoretical weight: 39.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:
Length: 346 amino acids
Theoretical weight: 39.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P05121 (Residues: 24-369; Coverage: 91%)
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:
Plasminogen activator inhibitor 1
Molecule details ›
Chain: B
Length: 33 amino acids
Theoretical weight: 3.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Length: 33 amino acids
Theoretical weight: 3.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P05121 (Residues: 370-402; Coverage: 9%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SIEMENS
Spacegroup:
C2
Expression system: Escherichia coli
