PDBe 9ilb

X-ray diffraction
2.28Å resolution

HUMAN INTERLEUKIN-1 BETA

Released:
Source organism: Homo sapiens
Primary publication:
Disordered water within a hydrophobic protein cavity visualized by x-ray crystallography.
Proc. Natl. Acad. Sci. U.S.A. 96 103-8 (1999)
PMID: 9874779

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interleukin-1 beta Chain: A
Molecule details ›
Chain: A
Length: 153 amino acids
Theoretical weight: 17.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01584 (Residues: 117-269; Coverage: 57%)
Gene names: IL1B, IL1F2
Sequence domains: Interleukin-1 / 18
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P43
Unit cell:
a: 55.02Å b: 55.02Å c: 77.16Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.157 0.157 0.21
Expression system: Escherichia coli