› 9ins

X-ray diffraction
1.7Å resolution

MONOVALENT CATION BINDING IN CUBIC INSULIN CRYSTALS

Released:
DOI: 10.2210/pdb9ins/pdb
PDB 9ins coloured by chain and viewed from the front.
PDB 9ins coloured by chain and viewed from the side.
PDB 9ins coloured by chain and viewed from the top.
Source organism: Sus scrofa
Entry authors: Badger J, Dodson GG

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
hetero tetramer
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Insulin A chain Chain: A
Molecule details ›
Chain: A
Length: 21 amino acids
Theoretical weight: 2.38 KDa
Source organism: Sus scrofa
Expression system: Not provided
UniProt:
  • Canonical: P01315 (Residues: 88-108; Coverage: 25%)
Gene name: INS
Insulin B chain Chain: B
Molecule details ›
Chain: B
Length: 30 amino acids
Theoretical weight: 3.4 KDa
Source organism: Sus scrofa
Expression system: Not provided
UniProt:
  • Canonical: P01315 (Residues: 25-54; Coverage: 36%)
Gene name: INS

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: I213
Unit cell:
a: 78.9Å b: 78.9Å c: 78.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.178 not available not available
Expression system: Not provided

Quick links

Citations

16 citation in other articles

Protein-protein interaction at crystal contacts.
Janin et al. (1995)
15 more

14 mentions without citation

In Quest for Improved Drugs against Diabetes: The Added Value of X-ray Powder Diffraction Methods.
Karavassili et al. (2017)
13 more