› 8y9x

X-ray diffraction
2Å resolution

Crystal structure of the complex of lactoperoxidase with four inorganic substrates, SCN, I, Br and Cl

Released:
DOI: 10.2210/pdb8y9x/pdb
PDB entry 8y9x coloured by chain, front view.
PDB entry 8y9x coloured by chain, side view.
PDB entry 8y9x coloured by chain, top view.
Source organism: Bos taurus
Entry authors: Viswanathan V, Singh AK, Pandey N, Sinha M, Kaur P, Sharma S, Singh TP

Function and Biology Details

Reaction catalysed: 
2 phenolic donor + H(2)O(2) = 2 phenoxyl radical of the donor + 2 H(2)O
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160329 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lactoperoxidase Chain: A
Molecule details ›
Chain: A
Length: 595 amino acids
Theoretical weight: 67.77 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P80025 (Residues: 118-712; Coverage: 86%)
Gene name: LPO
Sequence domains: Animal haem peroxidase

Ligands and Environments


Cofactor: Ligand HEM 1 x HEM
7 bound ligands:
Ligand CA 1 x CA
Ligand IOD 11 x IOD
Ligand BR 1 x BR
Ligand CL 1 x CL
Ligand PEG 7 x PEG
Ligand SCN 5 x SCN
Ligand NAG 6 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P21
Unit cell:
a: 53.35Å b: 80.332Å c: 73.391Å
α: 90° β: 103.94° γ: 90°
R-values:
R R work R free
0.153 0.151 0.195

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