PDB 8u4l structure summary ‹ Protein Data Bank in Europe (PDBe)

Function and Biology Details

Reaction catalysed:

ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate

Biochemical function:

not assigned

Biological process:

not assigned

Cellular component:

not assigned

Structure analysis Details

Assembly composition:

hetero trimer (preferred)

PDBe Complex ID:

PDB-CPX-241247 (preferred)

Entry contents:

3 distinct polypeptide molecules

Macromolecules (8 distinct):

Receptor tyrosine-protein kinase erbB-4 Chain: A

Molecule details ›

Chain: A
Length: 609 amino acids
Theoretical weight: 67.91 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:

Canonical: Q15303 (Residues: 26-634; Coverage: 48%)

Gene names: ERBB4, HER4
Sequence domains:

Receptor tyrosine-protein kinase erbB-2 Chain: B

Molecule details ›

Chain: B
Length: 606 amino acids
Theoretical weight: 66.89 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:

Canonical: P04626 (Residues: 24-629; Coverage: 49%)

Gene names: ERBB2, HER2, MLN19, NEU, NGL
Sequence domains:

Neuregulin-1 Chain: C

Molecule details ›

Chain: C
Length: 52 amino acids
Theoretical weight: 5.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt: