› 8tzl

Electron Microscopy
3.55Å resolution

Cryo-EM structure of Vibrio cholerae FtsE/FtsX/EnvC complex, full-length

Released:
DOI: 10.2210/pdb8tzl/pdb
PDB entry 8tzl coloured by chain, front view.
PDB entry 8tzl coloured by chain, side view.
PDB entry 8tzl coloured by chain, top view.
Source organism: Vibrio cholerae
Primary publication:
Structural insights into the FtsEX-EnvC complex regulation on septal peptidoglycan hydrolysis in Vibrio cholerae.
Hao A, Suo Y, Lee SY
Structure (2023)
PMID: 38070498
Related structures: EMD-41762

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-236602 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Cell division ATP-binding protein FtsE Chains: A, B
Molecule details ›
Chains: A, B
Length: 232 amino acids
Theoretical weight: 25.88 KDa
Source organism: Vibrio cholerae
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A085R4L6 (Residues: 2-224; Coverage: 100%)
Gene names: BC353_10980, D6U24_16490, ERS013200_01646, EYB64_19995, F0M16_17140, FLM02_03075, ftsE
Sequence domains: ABC transporter
Cell division protein FtsX Chains: C, D
Molecule details ›
Chains: C, D
Length: 330 amino acids
Theoretical weight: 36.52 KDa
Source organism: Vibrio cholerae
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A0H6I1B7 (Residues: 1-330; Coverage: 100%)
Gene names: BC353_10975, D6U24_16485, FLM02_03070, ftsX
Sequence domains:
Peptidase M23 domain-containing protein Chain: E
Molecule details ›
Chain: E
Length: 382 amino acids
Theoretical weight: 43.41 KDa
Source organism: Vibrio cholerae
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A7Z7YE94 (Residues: 1-382; Coverage: 100%)
Gene name: EYB64_19165
Sequence domains: Peptidase family M23

Ligands and Environments

2 bound ligands:
Ligand MG 2 x MG
Ligand ADP 2 x ADP
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.55Å
Relevant EMDB volumes: EMD-41762
Expression system: Escherichia coli

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