› 8q2w

X-ray diffraction
1.41Å resolution

Crystal structure of YTHDC1 in complex with Compound 8 (CS_01)

Released:
DOI: 10.2210/pdb8q2w/pdb
PDB entry 8q2w coloured by chain, front view.
PDB entry 8q2w coloured by chain, side view.
PDB entry 8q2w coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Bedi RK, Zalesak F, Caflisch A

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188634 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
YTH domain-containing protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 166 amino acids
Theoretical weight: 18.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96MU7 (Residues: 345-509; Coverage: 23%)
Gene names: KIAA1966, YT521, YTHDC1
Sequence domains: YT521-B-like domain

Ligands and Environments

2 bound ligands:
Ligand IUZ 2 x IUZ
Ligand SO4 7 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P21
Unit cell:
a: 39.87Å b: 103.07Å c: 42.03Å
α: 90° β: 104.75° γ: 90°
R-values:
R R work R free
0.192 0.191 0.206
Expression system: Escherichia coli

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