› 8izr

Electron Microscopy
3.62Å resolution

Multidrug resistance-associated protein 3

Released:
DOI: 10.2210/pdb8izr/pdb
PDB entry 8izr coloured by chain, front view.
PDB entry 8izr coloured by chain, side view.
PDB entry 8izr coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Yun CH, Gao HM
Related structures: EMD-35869

Function and Biology Details

Reactions catalysed: 
ATP + H(2)O + xenobiotic(Side 1) = ADP + phosphate + xenobiotic(Side 2)
ATP + H(2)O + glutathione-S-conjugate(Side 1) = ADP + phosphate + glutathione-S-conjugate(Side 2)
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-238418 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ATP-binding cassette sub-family C member 2 Chain: A
Molecule details ›
Chain: A
Length: 1589 amino acids
Theoretical weight: 179.45 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q92887 (Residues: 1-1545; Coverage: 100%)
Gene names: ABCC2, CMOAT, CMOAT1, CMRP, MRP2
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.62Å
Relevant EMDB volumes: EMD-35869
Expression system: Homo sapiens

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