Structure analysis

DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DGTP (1 MILLIMOLAR) AND MGCL2 (5 MILLIMOLAR)

X-ray diffraction
2.8Å resolution
Source organism: Homo sapiens
Assembly composition:
hetero trimer (preferred)
Entry contents: 1 distinct polypeptide molecule
2 distinct DNA molecules

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero trimer
Accessible surface area: 19293.89 Å2
Buried surface area: 2330.76 Å2
Dissociation area: 600.2 Å2
Dissociation energy (ΔGdiss): 6.72 kcal/mol
Dissociation entropy (TΔSdiss): 8.88 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-122612

Macromolecules

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Name: DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3')
Representative chains: T
Source organism: Homo sapiens [9606]
Expression system: Not provided
Length: 8 nucleotides
Theoretical weight: 2.43 KDa

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Name: DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3')
Representative chains: P
Source organism: Homo sapiens [9606]
Expression system: Not provided
Length: 7 nucleotides
Theoretical weight: 2.11 KDa

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