› 8fg2

Electron Microscopy
6Å resolution

SARS-CoV-2 Nucleocapsid dimer structure determined from COVID-19 patients

Released:
DOI: 10.2210/pdb8fg2/pdb
PDB entry 8fg2 coloured by chain, front view.
PDB entry 8fg2 coloured by chain, side view.
PDB entry 8fg2 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural Insights of the SARS-CoV-2 Nucleocapsid Protein: Implications for the Inner-workings of Rapid Antigen Tests.
Casasanta MA, Jonaid GM, Kaylor L, Luqiu WY, DiCecco LA, Solares MJ, Berry S, Dearnaley WJ, Kelly DF
Microsc Microanal 29 649-657 (2023)
PMID: 37749713
Related structures: EMD-29072

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145015 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoprotein Chains: A, B
Molecule details ›
Chains: A, B
Length: 419 amino acids
Theoretical weight: 45.69 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P0DTC9 (Residues: 1-419; Coverage: 100%)
Gene name: N
Sequence domains: Coronavirus nucleocapsid

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 6Å
Relevant EMDB volumes: EMD-29072

Quick links

Citations

1 review citation

SARS-CoV-2 proteins structural studies using synchrotron radiation.
Kosenko et al. (2023)
1 other article

3 mentions without citation

Overview of Nucleocapsid-Targeting Vaccines against COVID-19.
Rak et al. (2023)
2 more