X-ray diffraction
2.5Å resolution

The crystal structure of the I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with compound SJ001023044

Entry authors: Cuypers MG, Slavish JP, Rankovic Z, White SW

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Protein PA-X Chain: A
Molecule details ›
Chain: A
Length: 197 amino acids
Theoretical weight: 23.14 KDa
Source organism: Influenza A virus (A/Luxembourg/43/2009(H1N1))
Expression system: Escherichia coli
  • Canonical: C6H0Y9 (Residues: 1-50, 73-196; Coverage: 43%)
Gene name: PA
Sequence domains: Influenza RNA-dependent RNA polymerase subunit PA

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: I422
Unit cell:
a: 88.837Å b: 88.837Å c: 133.209Å
α: 90° β: 90° γ: 90°
R R work R free
0.229 0.227 0.263
Expression system: Escherichia coli