› 8dqs

X-ray diffraction
2.45Å resolution

The crystal structure of wild type PA endonuclease (2009/H1N1/CALIFORNIA) in complex with compound SJ001023032

Released:
DOI: 10.2210/pdb8dqs/pdb
PDB entry 8dqs coloured by chain, front view.
PDB entry 8dqs coloured by chain, side view.
PDB entry 8dqs coloured by chain, top view.
Source organism: Influenza A virus
Entry authors: Cuypers MG, Slavish JP, Rankovic Z, White SW

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-111579 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein PA-X Chain: A
Molecule details ›
Chain: A
Length: 197 amino acids
Theoretical weight: 23.15 KDa
Source organism: Influenza A virus
Expression system: Escherichia coli
UniProt:
  • Canonical: C6H0Y9 (Residues: 1-50, 73-196; Coverage: 43%)
Gene name: PA
Sequence domains: Influenza RNA-dependent RNA polymerase subunit PA

Ligands and Environments

3 bound ligands:
Ligand MN 2 x MN
Ligand T8I 1 x T8I
Ligand QQ4 1 x QQ4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: I422
Unit cell:
a: 88.782Å b: 88.782Å c: 135.117Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.209 0.207 0.245
Expression system: Escherichia coli

Quick links