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› 8dba

X-ray diffraction
3.5Å resolution

Crystal structure of dodecameric KaiC

Released:
DOI: 10.2210/pdb8dba/pdb
PDB entry 8dba coloured by chain, front view.
PDB entry 8dba coloured by chain, side view.
PDB entry 8dba coloured by chain, top view.
Source organism: Cereibacter sphaeroides
Primary publication:
From primordial clocks to circadian oscillators.
Pitsawong W, Pádua RAP, Grant T, Hoemberger M, Otten R, Bradshaw N, Grigorieff N, Kern D
OpenAccess logo Nature (2023)
PMID: 36949197

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dodecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-256285 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Circadian clock protein KaiC Chains: A, B, C, D, E, F, G, H, I, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 568 amino acids
Theoretical weight: 62.58 KDa
Source organism: Cereibacter sphaeroides
Expression system: Escherichia coli BL21(DE3)

Ligands and Environments

2 bound ligands:
Ligand ADP 24 x ADP
Ligand MG 23 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: P1
Unit cell:
a: 105.11Å b: 136.09Å c: 146.2Å
α: 93.13° β: 94.43° γ: 108.09°
R-values:
R R work R free
0.236 0.236 0.279
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

The inner workings of an ancient biological clock.
Fang et al. (2024)
1 more

1 mention without citation

From primordial clocks to circadian oscillators.
Pitsawong et al. (2023)