› 7z7i

Electron Microscopy
3.5Å resolution

Structure of ADP-ribosylated F-actin

Released:
DOI: 10.2210/pdb7z7i/pdb
PDB entry 7z7i coloured by chain, front view.
PDB entry 7z7i coloured by chain, side view.
PDB entry 7z7i coloured by chain, top view.
Source organism: Oryctolagus cuniculus
Primary publication:
Mechanism of threonine ADP-ribosylation of F-actin by a Tc toxin.
Belyy A, Lindemann F, Roderer D, Funk J, Bardiaux B, Protze J, Bieling P, Oschkinat H, Raunser S
Nat Commun 13 4202 (2022)
PMID: 35858890
Related structures: EMD-14533

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159326 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Actin, alpha skeletal muscle Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 377 amino acids
Theoretical weight: 42.11 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P68135 (Residues: 1-377; Coverage: 100%)
Gene names: ACTA, ACTA1
Sequence domains: Actin

Ligands and Environments

3 bound ligands:
Ligand ADP 5 x ADP
Ligand MG 5 x MG
Ligand APR 5 x APR
1 modified residue:
Ligand HIC 5 x HIC

Experiments and Validation Details

Entry percentile scores
Resolution: 3.5Å
Relevant EMDB volumes: EMD-14533

Quick links

Citations

6 citation in other articles

Molecular basis of threonine ADP-ribosylation of ubiquitin by bacterial ARTs.
Tan et al. (2023)
5 more