› 7vqi

Solution NMR

Solution NMR structure of Pseudomonas aeruginosa Lipopolysaccharide (LPS) Bicelle bound VR18 Antimicrobial Peptide

Released:
DOI: 10.2210/pdb7vqi/pdb
PDB entry 7vqi coloured by chain, ensemble of 20 models, front view.
PDB entry 7vqi coloured by chain, ensemble of 20 models, side view.
PDB entry 7vqi coloured by chain, ensemble of 20 models, top view.
Source organism: synthetic construct
Primary publication:
A rationally designed synthetic antimicrobial peptide against Pseudomonas-associated corneal keratitis: Structure-function correlation.
Mohid SA, Sharma P, Alghalayini A, Saini T, Datta D, Willcox MDP, Ali H, Raha S, Singha A, Lee D, Sahoo N, Cranfield CG, Roy S, Bhunia A
Biophys Chem 286 106802 (2022)
PMID: 35605494

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169009 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
VAL-ALA-ARG-GLY-TRP-GLY-ARG-LYS-CYS-PRO-LEU-PHE-GLY-LYS-ASN-LYS-SER-ARG (VR18) Chain: A
Molecule details ›
Chain: A
Length: 18 amino acids
Theoretical weight: 2.07 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 41%
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

2 review citations

Advances of Antimicrobial Peptide-Based Biomaterials for the Treatment of Bacterial Infections.
Li et al. (2023)
1 more

1 mention without citation

A rationally designed synthetic antimicrobial peptide against Pseudomonas-associated corneal keratitis: Structure-function correlation.
Mohid et al. (2022)