X-ray diffraction
2.47Å resolution

Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in Complex with L-Proline

Source organism: Toxoplasma gondii
Entry authors: Manickam Y, Malhotra N, Sharma A

Function and Biology Details

Reaction catalysed:
ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro)
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
proline--tRNA ligase Chains: A, B
Molecule details ›
Chains: A, B
Length: 499 amino acids
Theoretical weight: 57.88 KDa
Source organism: Toxoplasma gondii
Expression system: Escherichia coli
  • Canonical: A0A7J6JUK2 (Residues: 215-711; Coverage: 70%)
Gene name: TGRH88_057780
Sequence domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P21
Unit cell:
a: 77.196Å b: 81.673Å c: 104.66Å
α: 90° β: 102.94° γ: 90°
R R work R free
0.169 0.167 0.219
Expression system: Escherichia coli