X-ray diffraction
4Å resolution

Crystal Structure of VpsR display novel dimeric architecture and c-di-GMP binding: mechanistic implications in oligomerization, ATPase activity and DNA binding.

Source organism: Vibrio cholerae
Entry authors: Chakrabortty T, Sen U

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Sigma-54 factor interaction domain-containing protein Chains: A, D
Molecule details ›
Chains: A, D
Length: 399 amino acids
Theoretical weight: 44.72 KDa
Source organism: Vibrio cholerae
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q9AQ41 (Residues: 1-382; Coverage: 86%)
Gene name: vpsR
Sequence domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P31
Unit cell:
a: 119.687Å b: 119.687Å c: 81.141Å
α: 90° β: 90° γ: 120°
R R work R free
0.245 0.242 0.28
Expression system: Escherichia coli BL21(DE3)