7ury

X-ray diffraction
2.64Å resolution

Tetradecameric hub domain of CaMKII beta

Released:
Source organism: Homo sapiens
Entry authors: Ozden C, Saha S, Samkutty A, Stratton MM, Garman SC, Perry SL

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetradecamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium/calmodulin-dependent protein kinase type II subunit beta Chains: A, B, C, D, E, F, G
Molecule details ›
Chains: A, B, C, D, E, F, G
Length: 137 amino acids
Theoretical weight: 15.59 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q13554 (Residues: 534-666; Coverage: 20%)
Gene names: CAM2, CAMK2, CAMK2B, CAMKB
Sequence domains: Calcium/calmodulin dependent protein kinase II association domain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-1
Spacegroup: C2221
Unit cell:
a: 105.712Å b: 182.795Å c: 110.521Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.205 0.204 0.235
Expression system: Escherichia coli BL21(DE3)