7ude

X-ray diffraction
1.1Å resolution

Horse liver alcohol dehydrogenase with NAD and trifluoroethanol at 125 K

Released:
Source organism: Equus caballus
Entry authors: Plapp BV, Gakhar L

Function and Biology Details

Reaction catalysed:
A primary alcohol + NAD(+) = an aldehyde + NADH
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alcohol dehydrogenase E chain Chains: A, B
Molecule details ›
Chains: A, B
Length: 374 amino acids
Theoretical weight: 39.85 KDa
Source organism: Equus caballus
UniProt:
  • Canonical: P00327 (Residues: 2-375; Coverage: 100%)
Sequence domains:

Ligands and Environments


Cofactor: Ligand NAJ 2 x NAJ
3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P1
Unit cell:
a: 44.28Å b: 51.18Å c: 92.59Å
α: 91.9° β: 103.02° γ: 109.89°
R-values:
R R work R free
0.134 0.133 0.16