› 7tx8

X-ray diffraction
2.51Å resolution

Long form D7 protein from Anopheles darlingi with U46619 and serotonin bound

Released:
DOI: 10.2210/pdb7tx8/pdb
PDB 7tx8 coloured by chain and viewed from the front.
PDB 7tx8 coloured by chain and viewed from the side.
PDB 7tx8 coloured by chain and viewed from the top.
Source organism: Anopheles darlingi
Primary publication:
Functional aspects of evolution in a cluster of salivary protein genes from mosquitoes.
Alvarenga PH, Dias DR, Xu X, Francischetti IMB, Gittis AG, Arp G, Garboczi DN, Ribeiro JMC, Andersen JF
Insect Biochem. Mol. Biol. 146 103785-103785 (2022)
PMID: 35568118

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Long form d7 salivary protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 297 amino acids
Theoretical weight: 34.89 KDa
Source organism: Anopheles darlingi
Expression system: Escherichia coli
UniProt:
  • Canonical: B6DDQ8 (Residues: 21-317; Coverage: 100%)

Ligands and Environments

2 bound ligands:
Ligand SRO 4 x SRO
Ligand PUC 4 x PUC
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P3121
Unit cell:
a: 98.06Å b: 98.06Å c: 273.93Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.22 0.218 0.266
Expression system: Escherichia coli

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