Function and Biology Details
Reaction catalysed:
Angiotensin II + H(2)O = angiotensin-(1-7) + L-phenylalanine
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-209666 (preferred)
Entry contents:
6 distinct polypeptide molecules
Macromolecules (6 distinct):
Processed angiotensin-converting enzyme 2
Molecule details ›
Chains: E, F
Length: 601 amino acids
Theoretical weight: 69.62 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
Sequence domains: Angiotensin-converting enzyme
Length: 601 amino acids
Theoretical weight: 69.62 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
- Canonical:
Q9BYF1 (Residues: 19-615; Coverage: 76%)
Sequence domains: Angiotensin-converting enzyme
Spike protein S1
Molecule details ›
Chains: I, S
Length: 216 amino acids
Theoretical weight: 24.74 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
Length: 216 amino acids
Theoretical weight: 24.74 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
- Canonical: P0DTC2 (Residues: 324-531; Coverage: 17%)
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
