7swx

Electron Microscopy
3.13Å resolution

SARS-CoV-2 Spike in complex with neutralizing Fab SARS2-57 (three down conformation)

Released:
Entry authors: Adams LJ, Fremont DH, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
Related structures: EMD-25488

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-225368 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1133 amino acids
Theoretical weight: 125.52 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 14-1146; Coverage: 90%)
Gene names: 2, S
Sequence domains:
SARS2-57 Fv heavy chain Chain: H
Molecule details ›
Chain: H
Length: 117 amino acids
Theoretical weight: 12.96 KDa
Source organism: Mus musculus
SARS2-57 Fv light chain Chain: L
Molecule details ›
Chain: L
Length: 112 amino acids
Theoretical weight: 12.38 KDa
Source organism: Mus musculus

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.13Å
Relevant EMDB volumes: EMD-25488
Expression system: Homo sapiens