Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134214 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Insulin receptor
Molecule details ›
Chains: A, B
Length: 1372 amino acids
Theoretical weight: 155.79 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 1372 amino acids
Theoretical weight: 155.79 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
- Canonical:
P15208 (Residues: 1-1372; Coverage: 100%)
Sequence domains:
Insulin B chain
Molecule details ›
Chains: C, D
Length: 30 amino acids
Theoretical weight: 3.43 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Insulin/IGF/Relaxin family
Length: 30 amino acids
Theoretical weight: 3.43 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: P01308 (Residues: 25-54; Coverage: 35%)
Sequence domains: Insulin/IGF/Relaxin family
Insulin A chain
Molecule details ›
Chains: E, F
Length: 21 amino acids
Theoretical weight: 2.43 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Length: 21 amino acids
Theoretical weight: 2.43 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: P01308 (Residues: 90-110; Coverage: 24%)
