X-ray diffraction
1.7Å resolution

Crystal structure of Vaccinia Virus decapping enzyme D9 in complex with m7GDP


Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Nudix hydrolase domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 221 amino acids
Theoretical weight: 26.1 KDa
Source organism: Vaccinia virus Western Reserve
Expression system: Escherichia coli BL21(DE3)
  • Canonical: L7QJE0 (Residues: 1-213; Coverage: 100%)
Gene names: D9R, VACV_BRZ_SERRO2_112, VACV_CTGV_ALEH2_114, VACV_CTGV_CG04_114, VACV_CTGV_CM01_114, VACV_CTGV_MI233-114, VACV_CTGV_VI04_114, VACV_TT10_141, VACV_TT11_141, VACV_TT12_141, VACV_TT8_141, VACV_TT9_141, VACV_VK01_RKI-141, VACV_VK02_RKI-118, VACV_VK08_RKI-134, VACV_VK12_RKI-147, VAC_IHDW1_116, VAC_TKT3_104, VAC_TKT4_104, VAC_TP3_119, VAC_TP5_119
Sequence domains: NUDIX domain

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: C2221
Unit cell:
a: 52.55Å b: 140.1Å c: 75.98Å
α: 90° β: 90° γ: 90°
R R work R free
0.195 0.193 0.224
Expression system: Escherichia coli BL21(DE3)