› 7s5l

X-ray diffraction
1.58Å resolution

Cembrene A synthase from Eleutherobia rubra

Released:
DOI: 10.2210/pdb7s5l/pdb
PDB entry 7s5l coloured by chain, front view.
PDB entry 7s5l coloured by chain, side view.
PDB entry 7s5l coloured by chain, top view.
Source organism: Eleutherobia rubra
Primary publication:
Ancient plant-like terpene biosynthesis in corals.
Burkhardt I, de Rond T, Chen PY, Moore BS
Nat Chem Biol 18 664-669 (2022)
PMID: 35606558

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-168766 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cembrene A synthase Chain: A
Molecule details ›
Chain: A
Length: 393 amino acids
Theoretical weight: 45.76 KDa
Source organism: Eleutherobia rubra
Expression system: Escherichia coli BL21(DE3)

Ligands and Environments

2 bound ligands:
Ligand CL 1 x CL
Ligand EDO 3 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: C2
Unit cell:
a: 85.689Å b: 101.649Å c: 46.342Å
α: 90° β: 90.596° γ: 90°
R-values:
R R work R free
0.163 0.162 0.192
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

Class II terpene cyclases: structures, mechanisms, and engineering.
Pan et al. (2024)
2 more

2 mentions without citation

AlphaFold predictions are valuable hypotheses and accelerate but do not replace experimental structure determination.
Terwilliger et al. (2024)
1 more