7rj1

X-ray diffraction
2.16Å resolution

Crystal structure of Aro7p chorismate mutase from Candida albicans, complex with L-Trp

Released:
Source organism: Candida albicans SC5314
Entry authors: Stogios PJ, Evdokimova E, Tan K, Di Leo R, Savchenko A, Joachimiak A, Satchell KJF, Center for Structural Genomics of Infectious Diseases (CSGID)

Function and Biology Details

Reaction catalysed:
Chorismate = prephenate
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chorismate mutase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 269 amino acids
Theoretical weight: 31.1 KDa
Source organism: Candida albicans SC5314
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q59TS4 (Residues: 1-268; Coverage: 100%)
Gene names: ARO7, CAALFM_C111500CA, orf19.8763

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P21
Unit cell:
a: 61.751Å b: 93.154Å c: 99.709Å
α: 90° β: 106.959° γ: 90°
R-values:
R R work R free
0.186 0.184 0.241
Expression system: Escherichia coli BL21(DE3)